Results 141 to 150 of about 31,331 (306)
HELIN Serials Affinity Group minutes for 4/26/11
Minutes of the Serials Affinity Group of the HELIN Consortium for April ...
HELIN Consortium. Serials Affinity Group
core
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
HELIN Serials Committee minutes for 10/06/09
Minutes of the Serials Committee of the HELIN Consortium for October ...
HELIN Consortium. Serials Committee
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
HELIN Serials Committee minutes for 11/19/02
Minutes of the Serials Committee of the HELIN Consortium for November ...
HELIN Consortium. Serials Committee
core
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
HELIN Serials Committee minutes for 12/09/97
Minutes of the Serials Committee of the HELIN Consortium for December ...
HELIN Consortium. Serials Committee
core
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
A Look at Librarianship through the Lens of an Academic Library Serials Review
Talk to any librarian or library vendor and you’ll hear the same thing – the global economic downturn is hitting hard. Libraries everywhere are taking an axe to their collections; libraries are cutting book budgets, canceling serials subscriptions ...
Annette Day
doaj

