Results 171 to 180 of about 24,424 (312)

Film Serials and the American Cinema, 1910-1940

open access: yes
Before the advent of television, cinema offered serialized films as a source of weekly entertainment. This book traces the history from the days of silent screen heroines to the sound era's daring adventure serials, unearthing a thriving film culture ...
Brasch, Ilka
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Dynamics of double bubbles under the driving of burst ultrasound. [PDF]

open access: yesUltrason Sonochem, 2022
Wang X   +4 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Artificial Intelligence-Enabled 8-Channel ECG Diagnosing of Abnormalities with Wide QRS Complexes. [PDF]

open access: yesHealth Data Sci
Zhu H   +16 more
europepmc   +1 more source

Dispersing the Serials Collection and Measuring Paper: Cooperative Storage Efforts and Legacy Journals Management in a University Library

open access: yes, 2015
This article discusses workflows involved with contributing print journal back runs to scanning\ud and storage efforts. The purpose of these efforts was to alleviate space problems in a library\ud by consolidating stacks that were formerly used to house ...
Rogers, Tyler
core  

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