Results 141 to 150 of about 7,591,914 (316)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Comparative Analysis of Podcasts and Tv Fiction Series. Case Studies in Spain and the United States
Sound fiction genre takes a relevant position after the irruption of American productions such as Serial in the year 2014, whose success boosted its emission in other media as a series with the same title offered by HBO.
Silvia Olmedo Salar +1 more
doaj
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Littlefield Organ Series presents the Halloween Organ Recital October 26, 2013
Concert ProgramLittlefield Organ Series presents the Halloween Organ Recital October 26 ...
Littlefield Organ Series
core
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Sleep apnoea syndrome: how will physiologic knowledge position personalised medicine? [PDF]
F. Sériès
doaj
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Title Page of Mythological Papyri: Bollingen Series XL-3 Edited By Natacha Rambova
Text document title page of Mythological Papyri. Bollingen Series XL-3 Introduction by Alexandre Piankoff, Edited by Natacha RambovaConverted from .jpg to .pdf for ...
Alexandre Piankoff, Natacha Rambova
core
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source

