Results 161 to 170 of about 7,221,536 (339)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Concurrent inguinal hernia repair during robotic radical prostatectomy: a systematic review and meta-analysis. [PDF]

Hernia
Bruinsma J, Moynagh N, Mac Curtain BM, Clausen NA, Qian W, Elfaki M, Deshwal A, Nikolenko R, Haidaran I, Temperley HC, Ng ZQ.   +10 more
europepmc   +1 more source

The Naples warped hard chine hulls systematic series

, 2017
Fabio De Luca, Claudio Pensa
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

System Change Investing

Cadmus, 2021
Frank Dixon
doaj  

Bearing Anomaly Detection Method Based on Multimodal Fusion and Self-Adversarial Learning. [PDF]

Sensors (Basel)
Liu H, Qin Y, Tu D.
europepmc   +1 more source

Implementation and Analysis of an Improved Series-Loaded Resonant DC–DC Converter Operating Above Resonance for Battery Chargers

, 2009
Ying-Chun Chuang, Yu‐Lung Ke, Hung-Shiang Chuang, Hung-Kun Chen   +3 more
openalex   +1 more source

Long time series from the English Lake District: Irradiance‐dependent phytoplankton dynamics during the spring maximum [PDF]

, 1991
Patrick J. Neale, J. F. Talling, S. I. Heaney, C. S. Reynolds, John Lund   +4 more
openalex   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source