Results 41 to 50 of about 791,308 (312)

Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea [PDF]

, 2012
: BACKGROUND: Monitoring drug resistance in Mycobacterium tuberculosis is essential to curb the spread of tuberculosis (TB). Unfortunately, drug susceptibility testing is currently not available in Papua New Guinea (PNG) and that impairs TB control in ...
Gagneux, S., Siba Peter, Beck, H. P., Hans-Peter Beck, Beck Hans-Peter, Carter Robyn, Paul Harino, Harino, P., Carter, R., Serej Ley, Ley Serej, Siba, P., Gagneux Sebastien, Borrell Sonia, Coscolla Mireia, Mireia Coscolla, Ballif Marie, Stefan Niemann, Ley, S., Marie Ballif, Coulter, C., Robyn Carter, Coulter Christopher, Christopher Coulter, Ballif, M., Peter Siba, Niemann, S., Harino Paul, Niemann Stefan, Sebastien Gagneux, Phuanukoonnon, S., Borrell, S., Coscolla, M., Sonia Borrell, Suparat Phuanukoonnon, Phuanukoonnon Suparat   +35 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Calculation of the Electronic Parameters of an Al/DNA/p-Si Schottky Barrier Diode Influenced by Alpha Radiation

Sensors, 2015
Many types of materials such as inorganic semiconductors have been employed as detectors for nuclear radiation, the importance of which has increased significantly due to recent nuclear catastrophes. Despite the many advantages of this type of materials,
Hassan Maktuff Jaber Al-Ta'ii, Yusoff Mohd Amin, Vengadesh Periasamy   +2 more
doaj   +1 more source

Intermediate-type vancomycin resistance (VISA) in genetically-distinct Staphylococcus aureus isolates is linked to specific, reversible metabolic alterations. [PDF]

PLoS ONE, 2014
Intermediate (VISA-type) vancomycin resistance in Staphylococcus aureus has been associated with a range of physiologic and genetic alterations. Previous work described the emergence of VISA-type resistance in two clonally-distinct series of isolates. In
Elizabeth L Alexander, Susana Gardete, Haim Y Bar, Martin T Wells, Alexander Tomasz, Kyu Y Rhee   +5 more
doaj   +1 more source

Influence of the Assembly Method on the Cell Current Distribution of Series–Parallel Battery Packs Based on Connector Resistance

Frontiers in Energy Research, 2022
In order to meet the energy and power requirements of large-scale battery applications, lithium-ion batteries have to be connected in series and parallel to form various battery packs. However, unavoidable connector resistances cause the inconsistency of
Long Chang, Long Chang, Chen Ma, Chunxiao Luan, Zhezhe Sun, Cunyu Wang, Hongyu Li, Yulong Zhang, Xiangqi Liu   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

(a) Relation between series resistance and dose. (b) Relation between log series resistance and dose.

, 2016
(a) Relation between series resistance and dose. (b) Relation between log series resistance and dose.
Hassan Maktuff Jaber Al-Ta’ii (847710), Yusoff Mohd Amin (847711), Vengadesh Periasamy (569640)   +2 more
core   +1 more source

Evaluation of the fire resistance of steel-reinforced concretefilled steel tubular columns with a circular cross-section

, 2022
In the present investigation, an analysis of the fire resistance of the steel-reinforced concrete-filled steel tubular columns with circular cross-sections was carried out by means of numerical simulation.
Rojas Suárez, J P, Orjuela Abril, Martha Sofia, Pabón León, Jhon Antuny   +2 more
core   +1 more source

Fluctuations of a beam with clamped ends

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2015
In this paper we study the initial problem for the equation of a beam with clamped ends. Uniqueness, existence and stability theorems are proved for the problem in the classes of regular and generalized solutions.
Kamil B Sabitov
doaj   +1 more source