Results 71 to 80 of about 2,455,429 (307)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Amanda Camacho: Columbian Cut-Flower Worker [PDF]

, 2009
this story is part of ILRF\u27s Stories of Working Women series. In her testimony, Amanda Comacho describes the cut-flower industry, working conditions, and her daily life in Colombia.
International Labor Rights Forum
core   +1 more source

Hydrodynamic coupling and rotational mobilities near planar elastic membranes [PDF]

, 2018
We study theoretically and numerically the coupling and rotational hydrodynamic interactions between spherical particles near a planar elastic membrane that exhibits resistance towards shear and bending. Using a combination of the multipole expansion and
Abdallah Daddi-Moussa-Ider, Abramowitz M., Andreas M. Menzel, Conn A. R., Daddi Moussa Ider A., Dhont J. K. G., Fung Y.-C., Gardel M. L., Green A. E., Happel J., Hartmut Löwen, Kim S., Kohr M., Krüger T., Krüger T., Lauga E., Maciej Lisicki, Stephan Gekle, Zhu L.   +18 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Electrically Tunable Ideality Factor and Series Resistance of Gate-Controlled Graphene/Pentacene Schottky Junctions

IEEE Journal of the Electron Devices Society
Gate-tunable Schottky barrier diodes find many applications in logic transistors, photodiodes, and sensors. In this work, the electrical properties of Schottky barrier diodes with graphene/pentacene junctions and additional gates were investigated in ...
Tae Yoon Lee, Yoon-Jeong Kim, Seokhoon Ahn, Dae-Young Jeon   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The influence of methylammonium iodide concentration on the properties of perovskite solar cells

Energy Science & Engineering
This study focuses on improving the quality of MAPbI3‐based perovskite films by adjusting the concentration ratios of the methylammonium iodide (MAI) precursor using a two‐step sequential deposition method.
Naveen Kumar Elangovan, Raju Kannadasan, Max F. Savio, S. Vinson Joshua, Muhammad Faheem   +4 more
doaj   +1 more source

Algorithm Based on the Boole’s Integration Rule to Obtain Automatically the Five Solar Cell Parameters Within the One-Diode Solar Cell Model with an Executable Program

Energies
An algorithm has been implemented and it is provided in this article as an executable program to extract the five solar cell parameters within the one-diode solar cell model.
Victor-Tapio Rangel-Kuoppa
doaj   +1 more source

The Quantized Hall Insulator: A New Insulator in Two-Dimensions

, 1998
Quite generally, an insulator is theoretically defined by a vanishing conductivity tensor at the absolute zero of temperature. In classical insulators, such as band insulators, vanishing conductivities lead to diverging resistivities. In other insulators,
A Dykhne, AMM Pruisken, CH Lee, D Shahar, D Shahar, D Shahar, D Shahar, D. C. Tsui, D. Shahar, Don Monroe, E Shimshoni, E Shimshoni, HP Wei, HW Jiang, LP Pryadko, M Hilke, M. Hilke, O Viehweger, RJF Hughes, RL Willett, S Kivelson, S. H. Song, SC Zhang, SV Kravchenko, T Ando, T Sajoto, VJ Goldman, VJ Goldman, Y. H. Xie   +28 more
core   +1 more source