Results 11 to 20 of about 43,282 (204)
Myelodysplasia-associated mutations in serine/arginine-rich splicing factor SRSF2 lead to alternative splicing of CDC25C [PDF]
BMC Molecular Biology, 2016 Additional file 2: Figure S1.
Jeremy M. Stark +2 more
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Cells, 2022 Abiotic stresses profoundly affect plant growth and development and limit crop productivity. Pre-mRNA splicing is a major form of gene regulation that helps plants cope with various stresses.
Haroon Butt +6 more
doaj +4 more sources
Function of serine/arginine-rich splicing factors in hematopoiesis and hematopoietic malignancies
Cancer Cell InternationalThe serine/arginine-rich splicing factors (SRSFs) play an important role in regulating the alternative splicing of precursor RNA (pre-RNA). During this procedure, introns are removed from the pre-RNA, while the exons are accurately joined together to ...
Huifang Zhang +3 more
doaj +3 more sources
A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins) [PDF]
Genes & development, 2010 The serine/arginine-rich proteins (SR proteins) constitute a family of predominantly nuclear RNA-binding proteins that are present in all metazoan organisms and in plants.
Manley, J. L., Krainer, A. R.
core +5 more sources
BMC CancerBackground Dysregulated splicing events are a common phenomenon in cancer with the Serine-arginine-rich splicing factor (SRSF) family emerging as pivotal regulators of gene expression, exerting influence over constitutive and alternative splicing ...
Sakshi Sharma +5 more
doaj +3 more sources
An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor [PDF]
Endocrinology, 2002 The human IGF-I gene has six exons, four of which are alternatively spliced. Variations in splicing involving exon 5 may occur, depending on the tissue type and hormonal environment.
Chew, S. L. +6 more
core +4 more sources
Serine/arginine-rich splicing factors: the bridge linking alternative splicing and cancer [PDF]
International Journal of Biological Sciences, 2020 The serine/arginine-rich splicing factors (SRs) belong to the serine arginine-rich protein family, which plays an extremely important role in the splicing process of precursor RNA. The SRs recognize the splicing elements on precursor RNA, then recruit and assemble spliceosome to promote or inhibit the occurrence of splicing events.
Zheng, Xiang +6 more
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SRSF3 (serine/arginine-rich splicing factor 3) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012 Review on SRSF3 (serine/arginine-rich splicing factor 3), with data on DNA, on the protein encoded, and where the gene is implicated.
Jia, R, Zheng, ZM
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A Single Ancient Origin for Prototypical Serine/Arginine-Rich Splicing Factors [PDF]
Plant Physiology, 2011 Abstract Eukaryotic precursor mRNA splicing is a process involving a very complex RNA-protein edifice. Serine/arginine-rich (SR) proteins play essential roles in precursor mRNA constitutive and alternative splicing and have been suggested to be crucial in plant-specific forms of developmental regulation and environmental adaptation ...
Sophie, Califice +3 more
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RNA Biology, 2023 Often, alternative splicing is used by cancer cells to produce or increase proteins that promote growth and survival through alternative splicing. Although RNA-binding proteins are known to regulate alternative splicing events associated with tumorigenesis, their role in oesophageal cancer (EC) has rarely been explored.We analysed the expression ...
Ziqing Wei +8 more
openaire +3 more sources