Results 201 to 204 of about 43,282 (204)
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Small nucleolar RNP scleroderma autoantigens associate with phosphorylated serine/arginine splicing factors during apoptosis

Arthritis & Rheumatism, 2000
Proteins that are phosphorylated during apoptosis are commonly precipitated by autoantibodies found in the sera of patients with systemic lupus erythematosus. We sought to determine whether scleroderma autoantigens such as small nucleolar RNPs (snoRNP) also associate with phosphoproteins in response to various cellular stressors.We screened a panel of ...
K, Overzet   +7 more
openaire   +2 more sources

Regulation of gene expression programmes by serine–arginine rich splicing factors

Seminars in Cell & Developmental Biology, 2014
Serine-arginine rich splicing factors (SR proteins) are a family of RNA binding proteins that are essential for development in various model organisms. Although SR proteins are necessary for pre-mRNA splicing in metazoans, their binding is not limited to pre-RNA.
openaire   +2 more sources

The role of serine/arginine-rich splicing factors in regulation of pri-miRNA processing

2023
MicroRNAs (miRNAs) are short non-coding RNAs that play essential roles in RNA silencing and gene regulation. The human Microprocessor is the key factor to initiate miRNA biogenesis by cleaving primary microRNA (pri-miRNA). However, the Microprocessor cannot precisely and efficiently process all types of pri-miRNAs; thus, its cofactors assistance is ...
openaire   +2 more sources

Titration of serine/arginine (SR) splicing factors during adenoviral infection modulates E1A pre-mRNA alternative splicing.

RNA (New York, N.Y.), 1996
Alternative splicing of the adenovirus-2 E1A pre-mRNA involves the use of three 5' splice sites and is modulated during infection because the 13S mRNA and 9S mRNA reactions are predominant during the early and late periods, respectively. We had previously reproduced in vitro the 13S to 9S modulation with nuclear extracts isolated from infected HeLa ...
M, Himmelspach   +4 more
openaire   +1 more source

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