Results 191 to 200 of about 660,366 (297)

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

XPR1 downregulation inhibits hepatocellular carcinoma progression by suppressing serine metabolism. [PDF]

Redox Biol
Liao ZQ, Chen ZN, Lv YF, Zhang YY, Liu ZX, Deng ZQ, Liang QR, Zhang CB, Tang Q.   +8 more
europepmc   +1 more source

Oral delivery and formulation of salmon calcitonin: Protection from serine proteases with ovomucoids

, 2004
Rakhi B. Shah
openalex   +1 more source

Serine Transhydroxymethylase

, 1964
LaVerne Schirch, W. Terry Jenkins
openalex   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

Advanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang, Qingxin Si, Zhiguo Chen, Zhe Yu, Zhan Guo, Lu Wang, Weixi Li, Wangzhen Guo   +7 more
wiley   +1 more source

Junctional conductance of retinal AII amacrine cell electrical synapses is decreased by NMDA receptors. [PDF]

J Physiol
Cable C, Kuo SP, Newman EA.
europepmc   +1 more source

Serine Transhydroxymethylase

Journal of Biological Chemistry, 1968
L V Schirch, T Gross
openaire   +1 more source

Serine Transhydroxymethylase

Journal of Biological Chemistry, 1973
LaVerne Schirch, Michael Edmiston, Ming S. Chen, Donnetella Barra, Francesco Bossa, Leonard Hinds, Paolo Fasella   +6 more
openaire   +1 more source

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

Advanced Science, EarlyView.
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin, Mehdi Liauzun, Jacobo Solorzano, Morgane Le Bras, Christine Jean, Benjamin Fourneaux, Margaux Dore, Lea Fevrier, Ismahane Belhabib, Alexia Brunel, Cindy Neuzillet, Marion Larroque, Carine Joffre, Stephane Rocchi, Nicolas Fraunhoffer, Aurelie Perraud, Muriel Mathonnet, Vera Pancaldi, Laetitia Linares, Juan Iovanna, Nelson Dusetti, Ola Larsson, Remy Nicolle, Stephane Pyronnet, Corinne Bousquet, Yvan Martineau   +25 more
wiley   +1 more source

Repartitioning brain glucose: serine-nucleotide dependency sensitizes glioblastoma therapy. [PDF]

Signal Transduct Target Ther
Hong Y, Hua C, Wu M.
europepmc   +1 more source