Results 221 to 230 of about 951,429 (338)

Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation. [PDF]

Nat Commun
Upadhyay T, Woods EC, Dela Ahator S, Julin K, Faucher FF, Uddin MJ, Hollander MJ, Pedowitz NJ, Abegg D, Hammond I, Eke IE, Wang S, Chen S, Bennett JM, Jo J, Lentz CS, Adibekian A, Fellner M, Bogyo M.   +18 more
europepmc   +1 more source

MYC/TET3‐Regulated TMEM65 Activates OXPHOS‐SERPINB3 Pathway to Promote Progression and Cisplatin Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) remains a major challenge in breast cancer management as it lacks effective therapeutic targets. This study uncovers that MYC/TET3‐regulated mitochondrial inner‐membrane protein TMEM65 promotes TNBC progression and cisplatin resistance by activating the OXPHOS‐SERPINB3 pathway and reveals TMEM65 as a potential ...
Yin‐Ling Zhang, Min‐Ying Huang, Shao‐Ying Yang, Jia‐Yang Cai, Qian Zhao, Fang‐Lin Zhang, Xin Hu, Zhi‐Min Shao, Li Liao, A‐Yong Cao, Da‐Qiang Li   +10 more
wiley   +1 more source

Roles of the quantification of serine in the brain

EXCLI Journal : Experimental and Clinical Sciences
Jia-Meng Li, Ya-Zhi Bai, Shuang-Qing Zhang   +2 more
doaj   +1 more source

Editorial to the Special Issue "Glycine-(and D-Serine)-Related Neurotransmission: Promising Therapeutic Targets with Still Unsolved Problems". [PDF]

Biomedicines
Raiteri L.
europepmc   +1 more source

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source

Supplementation of serine in low-gossypol cottonseed meal-based diet improved egg white gelling and rheological properties by regulating ovomucin synthesis and magnum physiological function in laying hens

Journal of Integrative Agriculture
This study examined the effect of dietary serine (Ser) on egg white quality, ovomucin content of laying hens fed low-gossypol cottonseed meal (LCSM)-based diet and sought to explore the regulatory mechanism underlying the effects.
Jianmin Zhou, Yu Fu, Uchechukwu Edna Obianwuna, Jing Wang, Haijun Zhang, Xiubo Li, Guanghai Qi, Shugeng Wu   +7 more
doaj  

De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma. [PDF]

Cancer Res
Teisseire M, Sahu U, Parola J, Tsai MC, Vial V, Durivault J, Grépin R, Cormerais Y, Molina C, Gouraud A, Pagès G, Ben-Sahra I, Giuliano S.   +12 more
europepmc   +1 more source

Dynamic and Stable Core Microbiota Assist Plants in Enriching Selenium and Reducing Cadmium Absorption

Advanced Science, EarlyView.
During different developmental stages of plants in natural Se–Cd coexisting soils, there is a group of rhizosphere microorganisms with highly dynamic abundance. The abundance variation of these microorganisms is strongly positively correlated with available Se and strongly negatively correlated with available Cd.
Zheng Lei, Hua Zhang, Wenju Liu, Jiandong Sheng, Huan Zhang, Yin Wang, Yanni Tang, Huaxing Wang, Cuicui Ding, Wanqi Qiao, Yonghui Zhu, Guoyin Yang, Yihan Zhang, Zhuoyi Liu, Nanyu Zhou, Chengxiao Hu, Xiaohu Zhao   +16 more
wiley   +1 more source

Serine-Grafted Cu₂O Electrode Enabling Specific β-Hydroxybutyrate Detection by Surface Sensitization-Promoted Electrolysis in Amperometry. [PDF]

Langmuir
Lo TC, Wang WJ, Chen CY, Chang JC, Li WP.   +4 more
europepmc   +1 more source

SYNTHESIS OF SERINE

Journal of Biological Chemistry, 1936
Herbert E. Carter, Lee R. Schiltz
openaire   +2 more sources