Results 231 to 240 of about 130,012 (264)

PHGDH-related microcephalic dwarfism in two fetuses: Expanding the phenotypical spectrum of L-serine biosynthesis defect

open access: yesEuropean Journal of Medical Genetics, 2023
International audienceDefects in L-serine biosynthesis are a group of autosomal recessive diseases resulting in a wide phenotypic spectrum ranging from viable to lethal presentations and caused by variants in the three genes encoding the Lserine ...
Silvestre Cuinat, Philippe Loget
exaly   +2 more sources
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Studies on the biosynthesis of phosphatidyl serine

Biochimica et Biophysica Acta, 1959
Abstract 1. 1. A method is described for the determination of the radioactivity of [ 14 C]-phospholipids using a liquid scintillation counter. 2. 2. The incorporation of l -[ 14 C]serine into mitochondrial phospholipids was studied. CMP, ATP, CoASH, glutathione, glycerophosphate and magnesium ions were required for optimal incorporation. CTP
G, HUBSCHER, R R, DILS, W F, POVER
openaire   +2 more sources

The essential role of the phosphorylated pathway of serine biosynthesis inArabidopsis

open access: yesPlant Signaling and Behavior, 2013
[EN] In plants, 3 different pathways of serine biosynthesis have been described: the Glycolate pathway, which is associated with photorespiration, and 2 non-photorespiratory pathways, the Glycerate and the Phosphorylated pathways.
Jesus Muñoz-Bertomeu   +2 more
exaly   +2 more sources

The Enzymes of Serine Biosynthesis

Journal of Experimental Botany, 1969
Extracts of etiolated epicotyls of Pisum sativum have been shown to contain the enzymes necessary for the conversion of phosphohydroxypyruvate to serine. L-Glutamate acted as the amino donor in the formation of phosphoserine from phosphohydroxypyruvate while both L-alanine and L-aspartic acid were inactive.
J. C. SLAUGHTER, D. D. DAVIES
openaire   +1 more source

Enzymes of serine biosynthesis in Rhodopseudomonas capsulata

Archives of Biochemistry and Biophysics, 1973
Rhodopseudomonas capsulata has been shown to possess all the enzymatic activities of both the phosphorylated and nonphosphorylated pathways of serine biosynthesis. In addition there was an active serine hydroxymethyltransferase which catalyzed the reversible interconversion of serine and glycine.
L S, Schmidt, G A, Sojka
openaire   +2 more sources

On the phenotypic spectrum of serine biosynthesis defects

Journal of Inherited Metabolic Disease, 2016
AbstractL‐serine is a non‐essential amino acid that is de novo synthesized via the enzymes phosphoglycerate dehydrogenase (PGDH), phosphoserine aminotransferase (PSAT), and phosphoserine phosphatase (PSP). Besides its role in protein synthesis, L‐serine is a precursor of a number of important compounds.
Ayman W, El-Hattab   +6 more
openaire   +2 more sources

Biosynthesis of serine from glycine

Proceedings / Indian Academy of Sciences, 1958
(1) Various formate precursors studied, aid in the conversion of glycine to serinein vitro by rat liver enzymes to different degrees.
G. B. Nadkarni, A. Sreenivasan
openaire   +1 more source

On the biosynthesis of L-serine ethanolamine phosphate in the chicken

Biochimica et Biophysica Acta (BBA) - General Subjects, 1966
Abstract 1. 1. The biosynthesis of L -serine ethanolamine phosphate, a diester confined to fish, birds, reptile and amphibians, has been studied in chicken gut mucosa preparations. 2. 2. It has been shown that the diester is synthesised according to the overall reaction CDP-ethanolamine + L -serine → CMP + L -serine ethanolamine phosphate.
H, Rosenberg, A H, Ennor
openaire   +2 more sources

Changes in the pathways for serine biosynthesis in the developing amphibian

Comparative Biochemistry and Physiology, 1968
Abstract 1. 1. The pathways of serine biosynthesis utilizing either phosphorylated or nonphosphorylated intermediates, as well as the levels of activity of phosphoglycerate and d -glycerate dehydrogenases, have been investigated in tissues of frog at various stages of development. 2. 2.
H J, Sallach, E H, Kmiotek
openaire   +2 more sources

Serine Biosynthesis and Regulation in Haemophilus influenzae

Journal of Bacteriology, 1969
Nutritional mutants of Haemophilus influenzae requiring l -serine for growth were shown to be deficient in their capacity to synthesize serine-phosphate from 3-phosphoglycerate. On the basis of the correlation between this block and the requirement for an exogenous supply of the amino acid ...
L I, Pizer   +2 more
openaire   +2 more sources

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