Results 181 to 190 of about 268,204 (256)

Discovery of an autoinhibited conformation in mesotrypsin reveals a strategy for selective serine protease inhibition. [PDF]

open access: yesSci Adv
Coban M   +8 more
europepmc   +1 more source

Peptide Thioester and Triazole Derivatives Through On‐Resin Dual‐Modification of Peptide Thiosulfonates

open access: yesAngewandte Chemie International Edition, EarlyView.
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner   +5 more
wiley   +1 more source

Multivalent Tranexamic Acid (TXA) and Benzamidine Derivatives for Serine Protease Inhibition. [PDF]

open access: yesACS Pharmacol Transl Sci
Nallan Chakravarthula T   +6 more
europepmc   +1 more source

Arterial compliance is improved via enteral serine protease inhibition in experimental trauma/hemorrhagic shock. [PDF]

open access: yesFront Physiol
Li JB   +7 more
europepmc   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

open access: yesAnimal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen   +5 more
wiley   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

The serine protease HTRA1 targets tau fibrils and provides a proteolytic barrier against pathogenic protein conformations. [PDF]

open access: yesJ Biol Chem
Hagemeier B   +14 more
europepmc   +1 more source

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