Results 201 to 210 of about 268,204 (256)

Microbial Hydrolysates as Amino Acid Source in Cell Culture Media for Cellular Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The high cost of cultivation media remains one of the barriers to the commercialization of cultivated meat. Current serum‐free media reduce reliance on fetal bovine serum but only achieve modest cost savings. Especially at larger scales (> 20 m3), pharmaceutical‐grade amino acids and recombinant proteins remain major cost drivers.
Jelle C. Hoek, Jean‐Marc Daran, Marieke E. Klijn, Marcel A. Vieira‐Lara   +3 more
wiley   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Delivery of lipid nanoparticles containing small interfering RNA targeting transmembrane serine protease 4 in a human gastric cancer model using nude mice. [PDF]

Sci Rep
Tazawa H, Ishida Y, Suzuki T, Shimizu Y, Tashiro H.   +4 more
europepmc   +1 more source

Discovery and biochemical characterization of the D-aspartyl endopeptidase activity of the serine protease LACTB. [PDF]

J Biol Chem
Ito G, Utsunomiya-Tate N.
europepmc   +1 more source

Isolation and Characterization of a Biocontrol Serine Protease from <i>Pseudomonas aeruginosa</i> FZM498 Involved in Antagonistic Activity Against <i>Blastocystis</i> sp. Parasite. [PDF]

Biomolecules
Almilad FZ, Kotb E, Baghdadi HB, Hosin N, Alsaif HA, El-Badry AA.   +5 more
europepmc   +1 more source

The 3C-like serine protease activity of porcine astrovirus nsP1a/3 mediates mitochondrial apoptosis and MAVS cleavage to facilitate viral replication and antagonize type I interferon response. [PDF]

PLoS Pathog
Du Y, Lv Y, Feng X, Luo Y, Wei X, Shao S, Zhou Y, Ouyang K, Yin Y, Chen Y, Wei Z, Huang W, Qin Y.   +12 more
europepmc   +1 more source

Trichinella spiralis serine protease mediates larval invasion of gut epithelium via binding to CK8 and activating RhoA/ROCK1 pathway. [PDF]

PLoS Negl Trop Dis
Zheng WW, Zhang XZ, Cong PK, Zhang R, Long SR, Zhang X, Liu RD, Wang ZQ, Cui J.   +8 more
europepmc   +1 more source

Cathepsin L and transmembrane serine protease 11E mediate trypsin-independent entry of porcine deltacoronavirus into Huh7 cells. [PDF]

J Virol
Xiao W, Xiong Y, Wang Y, Li T, Chen C, Shi Y, Su G, Zhou Y, Xiao S, Fang L.   +9 more
europepmc   +1 more source

Corrigendum to "Serine protease inhibitors could be of benefit in the treatment of COVID-19 disease". [PDF]

Ther Adv Infect Dis
europepmc   +1 more source

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An Overview of Serine Proteases

Current Protocols in Protein Science, 2001
AbstractThis unit summarizes the families of serine proteases and their mechanism of catalysis. Methods for assays and determining substrate specificity are briefly described. The mode of action of commonly available inhibitors is also included.
openaire   +2 more sources