Additional file 3: of HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2
Roland Wagner +2 more
openalex +1 more source
C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independentin vivo [PDF]
Marieta M. Ruseva +3 more
openalex +1 more source
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen +9 more
wiley +1 more source
Mechanistic and Kinetic Insights into the Acylation Reaction of Hepatitis C Virus NS3/NS4A Serine Protease with NS4B/5A Substrate. [PDF]
Martínez-González JÁ +4 more
europepmc +1 more source
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
The cell-surface serine protease prostasin is lost during cervical squamous cell carcinogenesis. [PDF]
Lundgren JG, Flynn MG, List K.
europepmc +1 more source
Epidermal expression of serine protease, neuropsin (KLK8) in normal and pathological skin samples [PDF]
Katsuki Kuwae +6 more
openalex +1 more source
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai +15 more
wiley +1 more source
Identifying and controlling inactive and active conformations of a serine protease. [PDF]
Lee E +7 more
europepmc +1 more source

