Results 231 to 240 of about 422,331 (334)

Serine protease inhibitor dipetalogastin-like from Galleria mellonella is involved in insect immunity. [PDF]

Sci Rep
Kordaczuk J, Sułek M, Mak P, Pawlikowska-Pawlęga B, Wojda I.   +4 more
europepmc   +1 more source

Peer Review #1 of "In-silico prediction and modeling of the Entamoeba histolytica proteins: Serine-rich Entamoeba histolytica protein and 29 kDa Cysteine-rich protease (v0.1)"

, 2017
AL Milac
openalex   +2 more sources

Crystallization of a nonclassical Kazal-typeCarcinoscorpius rotundicaudaserine protease inhibitor, CrSPI-1, complexed with subtilisin [PDF]

, 2009
Rajesh T. Shenoy, Saravanan Thangamani, Bow Ho, J. Sivaraman, Jeak Ling Ding   +4 more
openalex   +1 more source

GSH as an A‐A Type Allosteric Activator of PKM2: Modulating Cancer Cell Homeostasis and Ferroptosis Susceptibility

Advanced Science, EarlyView.
Glutathione (GSH) defines oxidative balance, but can it directly tune central metabolism? The research reveals that GSH binds and potently activates pyruvate kniase M2 (PKM2), rewiring glycolysis and dictating ferroptosis sensitivity. Combining GSH depletion with PKM2 activation triggers mitochondrial damage and lipid peroxidation, profoundly ...
Tsan‐Jan Chen, Chi‐Jen Lo, Meng‐Jen Wu, Wei Yang Sit, Hsin‐Yu Hsu, Yi‐Cheng Huang, Chien‐Hung Lu, Yu‐Lun Chen, Wei‐Kai Fang, Shan‐Min Yang, Pei‐Lien Chen, Tokuko Haraguchi, Yasushi Hiraoka, Chun‐Yu Lin, Mei‐Ling Cheng, Muh‐Hwa Yang, Hsing‐Jien Kung, Wen‐Ching Wang   +17 more
wiley   +1 more source

Chemoenzymatically Synthesized O‐Acetylated GD3 Gangliosides to Examine Viral Receptor Specificities in a Cellular Context

Angewandte Chemie, EarlyView.
7‐O‐, 9‐O‐, and 7,9‐di‐O‐acetylated GD3 gangliosides can be prepared by chemical assembly of a tetrasaccharide as α‐glycosyl fluoride that is coupled to sphingosine using a glycosynthase, followed by O‐acetyl editing by coronaviral hemagglutinin‐esterases (HEs).
Zhiyong Zhang, Ruonan Liang, Kevin C. Hooijschuur, Robert P. de Vries, Zeshi Li, Geert‐Jan Boons   +5 more
wiley   +2 more sources

BjSP, a novel serine protease from Bothrops jararaca snake venom that degrades fibrinogen without forming fibrin clots

, 2018
Sante E. I. Carone, Danilo L. Menaldo, Marco Aurélio Sartim, Carolina P. Bernardes, Renato C. Caetano, Ronivaldo Rodrigues da Silva, Hamilton Cabral, Benedito Barraviera, Rui Seabra Ferreira, Suely Vilela Sampaio   +9 more
openalex   +2 more sources

Mutations Conferring Resistance to a Potent Hepatitis C Virus Serine Protease Inhibitor In Vitro [PDF]

, 2004
Liangjun Lu, Edward Tam, Kent D. Stewart, John T. Randolph, Ron Pithawalla, Wenping He, Peggy Huang, Larry L. Klein, Hongmei Mo, Akhteruzzaman Molla   +9 more
openalex   +1 more source

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Hatching of whipworm eggs induced by bacterial contact is serine-protease dependent. [PDF]

PLoS Pathog
Goulding D, Tolley C, Mkandawire TT, Doyle SR, Hart E, Airs PM, Grencis RK, Berriman M, Duque-Correa MA.   +8 more
europepmc   +2 more sources

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources