Results 291 to 300 of about 422,331 (334)

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Single-Chain Variable Fragments: Targeting Snake Venom Phospholipase A₂ and Serine Protease. [PDF]

Toxins (Basel)
Jia Y, Garcia A, Reyes E.
europepmc   +1 more source

Selenium‐Containing Tea‐Derived Peptides Activate Alcohol Dehydrogenase and Ameliorate Alcohol‐Induced Liver Injury by Modulating Oxidative Stress Homeostasis

Food Frontiers, EarlyView.
The graphical abstract summarizes the experimental workflow: (1) Preparation of selenium‐containing tea‐derived peptides (TSE‐PP) guided by ADH activation; (2) Purification and LC‐MS/MS identification of selenium‐modified peptides; (3) Molecular docking to reveal peptide‐ADH interactions; (4) Evaluation of hangover‐alleviating and hepatoprotective ...
Lixia Zan, Wenyi Zhang, Ning Gao, Jing Fu, Wengang Jin, Xiaoning Zhao, Xinsheng Li, Tianli Yue   +7 more
wiley   +1 more source

The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex. [PDF]

J Biol Chem
Tsamouri LP, Hsiao JC, Bachovchin DA.
europepmc   +1 more source

Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review

Food Frontiers, EarlyView.
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv, Yuanyuan Huang, Mokhtar Dabbour, Benjamin Kumah Mintah, Ronghai He, Haile Ma   +5 more
wiley   +1 more source

Macrocyclic Inhibitors Targeting the Prime Site of the Fibrinolytic Serine Protease Plasmin. [PDF]

ChemMedChem
Wiedemeyer SJA, Wu G, Lang-Henkel H, Whisstock JC, Law RHP, Steinmetzer T.   +5 more
europepmc   +1 more source

Borrelia burgdorferi serine protease HtrA is a pleiotropic regulator of stress response, motility, flagellar hemostasis, and infectivity. [PDF]

Commun Biol
Zhang K, Sze CW, Zhao H, Liu J, Li C.
europepmc   +1 more source

Neutrophils from patients with acquired neutropenia exhibit alterations in serine protease immunostaining and activity. [PDF]

Br J Haematol
Mazur A, Skrzeczynska-Moncznik J, Mavroudi I, Perraki CM, Korkmaz B, Papadaki HA, Cichy J.   +6 more
europepmc   +1 more source

Redox and solvent-stable alkaline serine protease from <i>Bacillus patagoniensis</i> DB-5: heterologous expression, properties, and biotechnological applications. [PDF]

Front Microbiol
Li Z, Xing Y, Liu P, Liao W, Miao L.
europepmc   +1 more source

Microsporidian Nosema bombycis secretes serine protease inhibitor to suppress host cell apoptosis via Caspase BmICE. [PDF]

PLoS Pathog
Ran M, Bao J, Li B, Shi Y, Yang W, Meng X, Chen J, Wei J, Long M, Li T, Li C, Pan G, Zhou Z.   +12 more
europepmc   +1 more source