Long-Range Electrostatics in Serine Proteases: Machine Learning-Driven Reaction Sampling Yields Insights for Enzyme Design. [PDF]
Zlobin A +4 more
europepmc +1 more source
The early communication stages between serine proteases and enterovirus capsids in the race for viral disintegration. [PDF]
Corre MH +5 more
europepmc +1 more source
Neutrophil-derived serine proteases induce FOXA2-mediated autophagy dysfunction and exacerbate colitis-associated carcinogenesis via protease activated receptor 2. [PDF]
Yuan J +11 more
europepmc +1 more source
A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation
The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf +4 more
wiley +1 more source
New advances in understanding inhibition of myeloperoxidase and neutrophil serine proteases by two families of staphylococcal innate immune evasion proteins. [PDF]
Herdendorf TJ +5 more
europepmc +1 more source
Structural Catalytic Core in Subtilisin-like Proteins and Its Comparison to Trypsin-like Serine Proteases and Alpha/Beta-Hydrolases. [PDF]
Denesyuk AI +3 more
europepmc +1 more source
<i>Entamoeba histolytica</i>-induced NETs are highly cytotoxic on hepatic and colonic cells due to serine proteases and myeloperoxidase activities. [PDF]
Jorge-Rosas F +4 more
europepmc +1 more source
Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target. [PDF]
Mall MA +5 more
europepmc +1 more source
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen +5 more
wiley +1 more source

