Results 181 to 190 of about 226,366 (284)

Evolution of the SARS-CoV-2 spike protein in utilizing host transmembrane serine proteases. [PDF]

iScience
Milewska A, Cofas-Vargas LF, Poma AB, Pyrć K.   +3 more
europepmc   +1 more source

The Activity of Metalloproteases and Serine Proteases in Various Organs after Leiurus macroctenus Envenomation. [PDF]

J Toxicol, 2023
Gunas V, Maievskyi O, Raksha N, Vovk T, Savchuk O, Shchypanskyi S, Gunas I.   +6 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

Serine Protease [PDF]

, 2020
openaire   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

Comparative immunodiagnostic evaluation of recombinant serine proteases from <i>Trichinella spiralis</i> and <i>Trichinella nativa</i> for early detection of trichinellosis. [PDF]

Vet World
Zhumalin A, Gajimuradova A, Bulashev A, Akibekov O, Syzdykova A, Gubaidullin N, Tosini F, Zhagipar F, Aydin A, Askarova N.   +9 more
europepmc   +1 more source

Serum mannan-binding lectin-associated serine proteases in early pregnancy for gestational diabetes in Chinese pregnant women. [PDF]

Front Endocrinol (Lausanne), 2023
Gao M, Li J, Zhang R, Li N, Li W, Zhang S, Wang P, Wang H, Fang Z, Yu Z, Hu G, Leng J, Yang X.   +12 more
europepmc   +1 more source

Machine‐Learning‐Assisted Impedance Component Analysis Enables Standardizable Surface Protein Analysis of Extracellular Vesicles Using Engineered Nanovesicles

Advanced Science, EarlyView.
This study establishes a universally applicable framework for vesicle surface analysis by combining engineered amyloid‐β‐displaying nanovesicles with machine‐learning‐optimized impedance spectroscopy. Equivalent‐circuit modeling reveals that membrane capacitance correlates with the surface protein states, enabling label‐free quantification of vesicle ...
Jaeyoon Song, Neethu Ramakrishnan, Sehyeon Kim, Huiseop Lee, Youngeun Kwon, Jinsik Kim   +5 more
wiley   +1 more source

Conserved structural topologies in RNase A-like and trypsin-like serine proteases: a sequence-based folding analysis. [PDF]

BMC Mol Cell Biol
Kabir KMA, Takahashi T, Kikuchi T.
europepmc   +1 more source

Correction: Simultaneous inhibition of two neutrophil serine proteases by the S. aureus innate immune evasion protein EapH2. [PDF]

J Biol Chem, 2023
Mishra N, Herdendorf TJ, Prakash O, Geisbrecht BV.   +3 more
europepmc   +1 more source