Results 31 to 40 of about 259,085 (245)

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins [PDF]

, 2006
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins
Scorilas, Andreas, Malm, Johan,, Courty, Yves, Ulf-Håkan Stenman, Lundwall, Åke,, Yousef, George M, Georgia Sotiropoulou, Lois J. Maltais, Talieri, Maroulio, Olsson, A Yvonne, Yousef, George, Talieri, M., Malm, Johan, Carsten Stephan, Stephan, Carsten, Blaber, M., Liija, H., Malm, J., Fritz, Hans, Blaber, Michael, Clements, Judith A, Lundwall, A., Lilja, Hans, Andreas Scorilas, Scorilas, A., Olsson, A. Yvonne, Hans Fritz, Judith A. Clements, Fritz, H., Lundwall, Åke, Constantina Petraki, Maltais, Lois J, Sotiropoulou, Georgia, Clements, J A, Clements, Judith, Lund University., Vimla Band, A. Yvonne Olsson, Band, Vimla, Maroulio Talieri, Stephan, C., Lilja, Hans,, Yousef, G M, Petraki, Constantina, Sotiropoulou, G., Courty, Y., Eleftherios P. Diamandis, Åke Lundwall, Michael Blaber, Diamandis, Eleftherios P, Hans Lilja, Stenman, Ulf-Hakan, Diamandis, E P, Maltais, L J, Petraki, C., George M. Yousef, Yves Courty, Olsson, A Y, Band, V., Maltais, Lois, Diamandis, Eleftherios, Johan Malm   +61 more
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Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?

Frontiers in Immunology, 2022
Several serine proteases have been linked to autoimmune disorders and tumour initiation although the mechanisms are not fully understood. Activation of the kynurenine pathway enzyme indoleamine-2,3-dioxygenase (IDO1) modulates cellular activity in the ...
Felix I. L. Clanchy, Felix I. L. Clanchy, Yi-Shu Huang, Joy Ogbechi, L. Gail Darlington, Richard O. Williams, Trevor W. Stone   +6 more
doaj   +1 more source

Malarial proteases and host cell egress: an 'emerging' cascade. [PDF]

, 2008
Malaria is a scourge of large swathes of the globe, stressing the need for a continuing effort to better understand the biology of its aetiological agent. Like all pathogens of the phylum Apicomplexa, the malaria parasite spends part of its life inside a
Blackman, Michael J
core   +1 more source

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation

EMBO Molecular Medicine, 2021
SPINK6 was identified in human skin as a cellular inhibitor of serine proteases of the KLK family. Airway serine proteases are required to cleave hemagglutinin (HA) of influenza A viruses (IAVs) to initiate an infection in the human airway.
Dong Wang, Cun Li, Man Chun Chiu, Yifei Yu, Xiaojuan Liu, Xiaoyu Zhao, Jingjing Huang, Zhongshan Cheng, Shuofeng Yuan, Vincent Poon, Jian‐Piao Cai, Hin Chu, Jasper Fuk‐Woo Chan, Kelvin Kai‐Wang To, Kwok Yung Yuen, Jie Zhou   +15 more
doaj   +1 more source

Genome-wide survey of prokaryotic serine proteases: Analysis of distribution and domain architectures of five serine protease families in prokaryotes

BMC Genomics, 2008
Background Serine proteases are one of the most abundant groups of proteolytic enzymes found in all the kingdoms of life. While studies have established significant roles for many prokaryotic serine proteases in several physiological processes, such as ...
Tripathi Lokesh P, Sowdhamini R
doaj   +1 more source

Purification and characterization of novel fibrinolytic proteases as potential antithrombotic agents from earthworm Perionyx excavatus [PDF]

, 2011
Six protease fractions, namely FI, FII, FIII-1, FIII-2, FIII-3 and FIV, were isolated from Perionyx excavatus earthworm biomass by acetone precipitation, followed by serial chromatography using anion exchange, hydrophobic interaction and size exclusion ...
Giang Duong, Tien Duy Ta, phan, T.T.B., Tram Phan, Tram Thi Bich Phan, Dung Nguyen, Broek, L.A.M., van den, Dung Thi Xuan Nguyen, Giang Thi Huong Duong, Tien Ta, Ta, T.D., Lambertus AM Van Den Broek, Nguyen, D.T.X.   +12 more
core   +1 more source

Airway proteolytic control of pneumococcal competence.

PLoS Pathogens, 2023
Streptococcus pneumoniae is an opportunistic pathogen that colonizes the upper respiratory tract asymptomatically and, upon invasion, can lead to severe diseases including otitis media, sinusitis, meningitis, bacteremia, and pneumonia.
Haley Echlin, Amy Iverson, Ugo Sardo, Jason W Rosch   +3 more
doaj   +1 more source

Independent Subtilases Expansions in Fungi Associated with Animals [PDF]

, 2011
Many socially important fungi encode an elevated number of subtilisin-like serine proteases, which have been shown to be involved in fungal mutualisms with grasses and in parasitism of insects, nematodes, plants, other fungi, and mammalian skin.
P. Szczesny, Muszewska, Anna, Taylor, John W., J. W. Taylor, Grynberg, Marcin, A. Muszewska, Szczesny, Pawel, M. Grynberg   +7 more
core   +2 more sources

Seprase: An overview of an important matrix serine protease [PDF]

, 2008
Seprase or Fibroblast Activation Protein (FAP) is an integral membrane serine peptidase, which has been shown to have gelatinase activity. Seprase has a dual function in tumour progression.
O\u27Brien, Pamela, O'Brien, Pamela, O'Connor, Brendan, O\u27Connor, Brendan   +3 more
core   +2 more sources

New insights into the evolution of subtilisin-like serine protease genes in Pezizomycotina

BMC Evolutionary Biology, 2010
Background Subtilisin-like serine proteases play an important role in pathogenic fungi during the penetration and colonization of their hosts. In this study, we perform an evolutionary analysis of the subtilisin-like serine protease genes of subphylum ...
Zhang Ying, Liang Lianming, Yu Zefen, Tian Baoyu, Dong Linqian, Yang Jinkui, Yu Li, Li Juan, Wang Xu, Zhang Keqin   +9 more
doaj   +1 more source