Results 211 to 220 of about 98,151 (252)
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Targeting Serine Proteases in Asthma
Current Topics in Medicinal Chemistry, 2006Leukocytes and lung structural cells contribute to the pathophysiology of asthma through the production of numerous mediators including serine proteases. Such proteases include mast cell tryptase and chymase; neutrophil elastase, cathepsin G and myeloblastin (proteinase 3); bronchial epithelial cell-derived transmembrane protease, serine 11D (human ...
Caroline, Guay +2 more
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Strategies for the inhibition of serine proteases
Cellular and Molecular Life Sciences, 2001Serine proteases have been shown to play a multifarious role in health and disease. As a result, there has been considerable interest in the design and development of synthetic inhibitors of these enzymes. In view of their diverse roles in biological processing events, one of the great challenges in such endeavours has been the need to produce ...
B, Walker, J F, Lynas
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Serine proteases and cardiac function
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2005The serine proteases of the trypsin superfamily are versatile enzymes involved in a variety of biological processes. In the cardiovascular system, the importance of these enzymes in blood coagulation, platelet activation, fibrinolysis, and thrombosis has been well established.
Qingyu, Wu +2 more
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A critical review on marine serine protease and its inhibitors: A new wave of drugs?
International Journal of Biological Macromolecules, 2021Mohsen Gozari +2 more
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Diarylethene-Based Photoswitchable Inhibitors of Serine Proteases
Angewandte Chemie - International Edition, 2021Anne Ulrich +2 more
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Cell surface–anchored serine proteases in cancer progression and metastasis
Cancer and Metastasis Reviews, 2019Karin List
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The epidermal barrier function is dependent on the serine protease CAP1/Prss8
Journal of Cell Biology, 2005Samuel Rotman +2 more
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