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Serine proteases of the complement system
Biochemical Society Transactions, 2000The complement system in blood plasma is a major mediator of innate immune defence. The function of complement is to recognize, then opsonize or lyse, particulate materials, including bacteria, yeasts and other microrganisms, host cell debris and altered host cells.
R B, Sim, A, Laich
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Targeting Serine Proteases in Asthma
Current Topics in Medicinal Chemistry, 2006Leukocytes and lung structural cells contribute to the pathophysiology of asthma through the production of numerous mediators including serine proteases. Such proteases include mast cell tryptase and chymase; neutrophil elastase, cathepsin G and myeloblastin (proteinase 3); bronchial epithelial cell-derived transmembrane protease, serine 11D (human ...
Caroline, Guay +2 more
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Unleashing the therapeutic potential of human kallikrein-related serine proteases
Nature Reviews Drug Discovery, 2015Eleftherios Diamandis +2 more
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Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration
Protein Science, 2008Mark Paetzel
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Cell surface–anchored serine proteases in cancer progression and metastasis
Cancer and Metastasis Reviews, 2019Karin List, List Karin
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Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
Nature Medicine, 2010Steffen Massberg +2 more
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