Results 171 to 180 of about 72,685 (290)

Biophysical and Functional Characterization of a Thermally Stable Bifunctional Serine Protease Inhibitor from <i>Cleome viscosa</i> Seeds. [PDF]

Int J Mol Sci
Radhakrishnan M, Senthilvadivelu V, Nadendla EK, Sivashanmugan K, Krishnasamy G.   +4 more
europepmc   +1 more source

Processing of mitochondrial precursor proteins [PDF]

, 1991
Arretz, Michael, Neupert, Walter, Schneider, Helmut, Wienhues, Ulla   +3 more
core  

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

Advanced Science, EarlyView.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

Inhibitors of Proteases: A Well-Grounded Strategy in Drug Development. [PDF]

Molecules
Previti S, Ettari R.
europepmc   +1 more source

An endogenous inhibitor of cysteine and serine proteinases from spleen [PDF]

FEBS Letters, 1982
Brzin, J., Kopitar, M., Ločnikar, P., Turk, V.   +3 more
openaire   +2 more sources

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Kazal-type serine protease inhibitors from Arabidopsis thaliana and Toxoplasma gondii exhibit antimicrobial activity against plant pathogens. [PDF]

Sci Rep
Sánchez MA, Strack KN, Mendoza-Morales LF, Ramos-Duarte VA, Pérez Sanchidrian E, Sander VA, Melina LB, Pieckenstain FL, Clemente M.   +8 more
europepmc   +1 more source

Proteinase-proteinase inhibitor imbalance in inflammation and multiple trauma with special amphasis on release of granulocytic lysosomal elastase [PDF]

, 1984
Dittmer, H., Duswald, Karl-Heimo, Elödi, P., Fritz, Hans, Jochum, Marianne   +4 more
core   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source