Results 251 to 260 of about 128,354 (367)

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

A Virtual Screening Approach to Evaluate the Multitarget Potential of a Chalcone Library with Binding Properties to Oligopeptidase B and Cysteine Proteinase B from <i>Leishmania (Viannia) braziliensis</i>. [PDF]

Int J Mol Sci
Monteiro PQ, Schaeffer E, da Silva AJM, Alves CR, Souza-Silva F.   +4 more
europepmc   +1 more source

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

, 1995
Sandra Schneider, C Schick, Kimberlee E Fish, Elizabeth M. Miller, J C Pena, S. Treter, Stephanie M. Hui, Gary A. Silverman   +7 more
openalex   +1 more source

Atypical Kunitz-Type Serine Proteinase Inhibitors Produced by the Ruminant Placenta1

Biology of Reproduction, 2004
J. MacLean, R. Roberts, Jonathan A Green
semanticscholar   +1 more source

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

Cancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu, Yixiao Xiong, Yuxin Zhang, Huifang Liang, Kun Cheng, Yuanxiang Lu, Guangzhen Cai, Yang Wu, Yunhui Fan, Xiaoping Chen, Hong Zhu, Zeyang Ding, Wanguang Zhang   +12 more
wiley   +1 more source

A major Toxoplasma serine protease inhibitor protects the parasite against gut-derived serine proteases and NETosis damage. [PDF]

J Biol Chem
Saffarian M, Romano JD, Grigg ME, Coppens I.   +3 more
europepmc   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Effects of a Proteinase Inhibitor from <i>Inga laurina</i> Seeds (ILTI) on <i>Aedes aegypti</i> Larval Development. [PDF]

J Xenobiot
Jacobowski A, Leite W, Júnior AM, Reis E, Pires L, Silva V, Rocha L, Arruda E, Franco O, Cardoso M, Hiane P, Macedo M.   +11 more
europepmc   +1 more source

Isolation and Characterization of porcine leukocyte elastase. [PDF]

, 1985
Geiger, Reinhard, Jochum, Marianne, Junk, A.   +2 more
core   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

Cancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu, Yingqi Zhao, Xin Zhang, Yuanhe Wang, Qiuchen Chen, Mingrong Zhang, Huan Sheng, Yuying Zhang, Jinyu Guo, Jun Li, Yuxuan Fan, Ziqing Wang, Yalun Li, Haoran Wang, Minjie Wei, Xiaoyun Hu, Huizhe Wu   +16 more
wiley   +1 more source