Results 1 to 10 of about 13,891 (213)

Preparation and evaluation of Brucella T4SS recombinant proteins in serodiagnosis of human brucellosis based on TMT-based proteomics technology [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionBrucellosis, a significant zoonotic infectious disease, poses a global health threat. Accurate and efficient diagnosis is crucial for prevention, control, and treatment of brucellosis. VirB proteins, components of the Type IV secretion system
Qi Wu, Chen Sun, Liping Guo, Yujia Xie, Jinpeng Zhang, Jinpeng Zhang, Dehui Yin, Dehui Yin   +7 more
doaj   +2 more sources

Simplified Point-of-Care Testing for Human Pythiosis: Development of a Whole-Blood-Based Lateral Flow Immunoassay [PDF]

Diagnostics
Background/Objectives: Human pythiosis, caused by Pythium insidiosum, is associated with severe morbidity and high mortality when diagnosis is delayed. Culture-based diagnosis is time-consuming and may be insensitive in clinical specimens, highlighting ...
Jidapa Szekely, Kitti Saelai, Sirida Youngchim, Siriporn Chongkae, Pornchanan Chanchay, Wiraphan Rakchang, Paramaporn Rattanaphan, Narongdet Kositpantawong   +7 more
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VLP-based indirect ELISA enables reliable sero-diagnosis and epidemiological monitoring of duck circovirus [PDF]

Frontiers in Veterinary Science
IntroductionDuck circovirus (DuCV) is an emerging immunosuppressive virus that causes growth retardation, feather loss, and increased susceptibility to secondary infections in ducks, leading to significant economic losses in the duck industry.
Shihua Qiu, Fangchao Guo, Lingyan Zhao, Zhaozhen Zhong, Zhaozhen Zhong, Yuancheng Wang   +5 more
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rMELEISH: A Novel Recombinant Multiepitope-Based Protein Applied to the Serodiagnosis of Both Canine and Human Visceral Leishmaniasis

Pathogens, 2023
Background: visceral leishmaniasis (VL) is a critical public health problem in over ninety countries. The control measures adopted in Brazil have been insufficient when it comes to preventing the spread of this overlooked disease.
Daniel Silva Dias, Juliana Martins Machado, Patrícia Aparecida Fernandes Ribeiro, Amanda Sanchez Machado, Fernanda Fonseca Ramos, Lais Moreira Nogueira, Ana Alice Maia Gonçalves, Luana de Sousa Ramos, Isadora Braga Gandra, Flaviane Silva Coutinho, Michelli dos Santos, Jonatas Oliveira da Silva, Miguel Angel Chávez-Fumagalli, Rafael Gonçalves Teixeira-Neto, Ana Thereza Chaves, Mariana Campos-da-Paz, Amanda A. Souza, Rodolfo Cordeiro Giunchetti, Sonia Maria Freitas, Sandra Lyon, Danielle Ferreira de Magalhães-Soares, Julia Angelica Gonçalves Silveira, Eduardo Sergio Silva, Eduardo Antonio Ferraz Coelho, Alexsandro Sobreira Galdino   +24 more
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Antibody Cross-Reactivity in Serodiagnosis of Lyme Disease

Antibodies, 2023
Lyme disease is a tick-borne disease caused by spirochetes belonging to the Borrelia burgdorferi sensu lato complex. The disease is characterized by a varied course; therefore, the basis for diagnosis is laboratory methods.
Weronika Grąźlewska, Lucyna Holec-Gąsior   +1 more
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Review on the Current Trends of Toxoplasmosis Serodiagnosis in Humans

Frontiers in Cellular and Infection Microbiology, 2020
Toxoplasmosis is a widely distributed zoonotic infection caused by the obligate intracellular apicomplexan parasite Toxoplasma gondii. It is mainly transmitted through the ingestion of oocysts shed by an infected cat acting as its definitive host.
Rochelle Haidee D. Ybañez, Adrian P. Ybañez, Yoshifumi Nishikawa   +2 more
doaj   +1 more source

Development of a Novel Enzyme-Linked Immunosorbent Assay and Lateral Flow Test System for Improved Serodiagnosis of Visceral Leishmaniasis in Different Areas of Endemicity

Microbiology Spectrum, 2023
Visceral leishmaniasis (VL) is caused by protozoan parasites of the Leishmania donovani complex and is one of the most prominent vector-borne infectious diseases with epidemic and mortality potential if not correctly diagnosed and treated.
Rouzbeh Mahdavi, Hosam Shams-Eldin, Sandra Witt, Andreas Latz, Daniela Heinz, Alba Fresco-Taboada, Cristina Aira, Marc P. Hübner, Dalia Sukyte, Alexander Visekruna, Henrique C. Teixeira, Elfadil Abass, Ulrich Steinhoff   +12 more
doaj   +1 more source

Identification of Immunogenic Linear B-Cell Epitopes in C. burnetii Outer Membrane Proteins Using Immunoinformatics Approaches Reveals Potential Targets of Persistent Infections

Pathogens, 2021
Coxiella burnetii is a global, highly infectious intracellular bacterium, able to infect a wide range of hosts and to persist for months in the environment. It is the etiological agent of Q fever—a zoonosis of global priority.
Sílvia da Silva Fontes, Fernanda de Moraes Maia, Laura Santa’Anna Ataides, Fernando Paiva Conte, Josué da Costa Lima-Junior, Tatiana Rozental, Matheus Ribeiro da Silva Assis, Adonai Alvino Pessoa Júnior, Jorlan Fernandes, Elba Regina Sampaio de Lemos, Rodrigo Nunes Rodrigues-da-Silva   +10 more
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Enzyme-linked immunosorbent assays using virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections

Emerging Microbes and Infections, 2020
The recent outbreaks of Zika virus (ZIKV) in flavivirus-endemic regions highlight the need for sensitive and specific serological tests. Previously we and others reported key fusion loop (FL) residues and/or BC loop (BCL) residues on dengue virus (DENV ...
Wen-Yang Tsai, Kaitlin Driesse, Jih-Jin Tsai, Szu-Chia Hsieh, Robert Sznajder Granat, Olivia Jenkins, Gwong-Jen Chang, Wei-Kung Wang   +7 more
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Immunological Cross-Reactivity of Proteins Extracted from the Oomycete Pythium insidiosum and the Fungus Basidiobolus ranarum Compromises the Detection Specificity of Immunodiagnostic Assays for Pythiosis

Journal of Fungi, 2021
Pythiosis, a life-threatening disease caused by Pythium insidiosum, has been increasingly diagnosed worldwide. A recently developed immunochromatographic test (ICT) enables the rapid diagnosis of pythiosis.
Tiwa Rotchanapreeda, Pattarana Sae-Chew, Tassanee Lohnoo, Wanta Yingyong, Thidarat Rujirawat, Yothin Kumsang, Penpan Payattikul, Chalisa Jaturapaktrarak, Akarin Intaramat, Watcharapol Pathomsakulwong, Chompoonek Yurayart, Theerapong Krajaejun   +11 more
doaj   +1 more source