Results 51 to 60 of about 89,599 (313)

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

Cell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner, Neda Dadgar, Anil Vaidya, Robert Simon, Clifton Fulmer, Hassan Siddiki, K. V. Narayanan Menon, Peter Liu, R. Matthew Walsh   +8 more
wiley   +1 more source

Assessment of Inter-Laboratory Differences in SARS-CoV-2 Consensus Genome Assemblies between Public Health Laboratories in Australia

Viruses, 2022
Whole-genome sequencing of viral isolates is critical for informing transmission patterns and for the ongoing evolution of pathogens, especially during a pandemic.
Charles S. P. Foster, Sacha Stelzer-Braid, Ira W. Deveson, Rowena A. Bull, Malinna Yeang, Jane-Phan Au, Mariana Ruiz Silva, Sebastiaan J. van Hal, Rebecca J. Rockett, Vitali Sintchenko, Ki Wook Kim, William D. Rawlinson   +11 more
doaj   +1 more source

Longitudinal Monitoring of SARS-CoV-2 IgM and IgG Seropositivity to Detect COVID-19. [PDF]

, 2020
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a novel beta-coronavirus that has recently emerged as the cause of the 2019 coronavirus pandemic (COVID-19).
Fitzgerald, Robert L, Hoffman, Melissa A, Kelner, Michael J, McLawhon, Ronald W, Reed, Sharon L, Suhandynata, Raymond T   +5 more
core  

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]

, 2018
It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel, Katz, Zachary, Ndung'u, Joseph Mathu, Picado, Albert, Redard Jacot, Maël, Schijman, Alejandro Gabriel, Sosa-Estani, Sergio Alejandro, Torrico, Faustino   +7 more
core   +1 more source

THE SPECIFICITY OF SEROLOGICAL PRECIPITATION [PDF]

Journal of Experimental Medicine, 1946
Precipitative mixing experiments have been conducted with the aid of a turbidimeter and a darkfield microscope. The results of these experiments, correlated with observations of macroscopic features, indicate that serological precipitation is largely governed by a highly specific mechanism except in the terminal period, when the operation of non ...
openaire   +6 more sources

Comprehensive, comparative evaluation of 25 automated SARS-CoV-2 serology assays

Microbiology Spectrum
The onset of the COVID-19 pandemic resulted in hundreds of in vitro devices coming to market, facilitated by regulatory authorities allowing “Emergency Use,” without a prior comprehensive evaluation of performance.
Wayne Dimech, Shannon Curley, Jing Jing Cai   +2 more
doaj   +1 more source

DNA Methylation of the ABO Promoter Underlies Loss of ABO Allelic Expression in a Significant Proportion of Leukemic Patients [PDF]

, 2009
Background: Loss of A, B and H antigens from the red blood cells of patients with myeloid malignancies is a frequent occurrence. Previously, we have reported alterations in ABH antigens on the red blood cells of 55% of patients with myeloid malignancies.
A Dobrovic, A Dobrovic, A Evdokiou, A Kahn, A Kuemmel, Alexander Dobrovic, C Limas, C Salmon, C Salmon, CH Buzin, D Ichikawa, Damian J. Hussey, Denise S. O'Keefe, DS O'Keefe, DS O'Keefe, DS O'Keefe, E Dabelsteen, E Dabelsteen, EJ Perlman, F Yamamoto, F Yamamoto, F Yamamoto, F Yamamoto, F Yamamoto, G Daniels, H Matsumoto, H Xu, I Orlow, J Frigola, J Moldvay, J Worm, JC Lee, JJ van Loghem, JS Lee, Jörg Hoheisel, KA Marsden, M Keinanen, M Welshinger, MC Eaton, PH Lange, PJ Fialkow, Q Liu, R Schoentag, RD Larsen, RR Race, S Gao, S Hirohashi, S Suciu, SA Miller, T Bianco, T Bianco, T Nakagoe, Tanya K. Day, TF Orntoft, Tina Bianco-Miotto, TK Wojdacz, Y Chihara, Y Hata, Y Kominato, Y Kominato, Z Xiong   +60 more
core   +15 more sources

Retrospective Study Investigating the Prevalence and Clinical Significance of Hepatitis B Virus Precore and Basal Core Promoter Variants

Canadian Journal of Gastroenterology and Hepatology, 2015
BACKGROUND: Hepatitis B virus (HBV) precore (PC) and basal core promoter (BCP) variants are well known; however, their prevalence in North America is unclear, especially among hepatitis B e antigen-negative patients.
Meaghan O’Brien, Adara Casselman, Gerry Smart, Ainsley Gretchen, Kelly Kaita, Kamran Kadkhoda   +5 more
doaj   +1 more source

Evaluation of the Potential Diagnostic Utility of the Determination of Selected Immunological and Molecular Parameters in Patients with Ovarian Cancer

Diagnostics, 2023
Ovarian cancer is one of the most serious challenges in modern gynaecological oncology. Due to its non-specific symptoms and the lack of an effective screening procedure to detect the disease at an early stage, ovarian cancer is still marked by a high ...
Aleksandra Englisz, Marta Smycz-Kubańska, Aleksandra Mielczarek-Palacz   +2 more
doaj   +1 more source

Estimation of World Seroprevalence of SARS-CoV-2 antibodies [PDF]

arXiv, 2022
In this paper, we estimate the seroprevalence against COVID-19 by country and derive the seroprevalence over the world. To estimate seroprevalence, we use serological surveys (also called the serosurveys) conducted within each country. When the serosurveys are incorporated to estimate world seroprevalence, there are two issues.
arxiv