Results 61 to 70 of about 89,599 (313)
Autosomal recessive hyper‐IgE syndrome due to DOCK8 deficiency: An adjunctive role for omalizumab
We report a rare case of AR‐HIES with DOCK8 deficiency in a young male that was successfully treated by infection management, skincare, diet elimination, and omalizumab. Abstract Autosomal recessive hyper‐IgE syndrome (AR‐HIES) is a rare primary immunodeficiency disorder characterized by high serum IgE levels, recurrent viral skin infections, severe ...
Kim Han Nguyen+8 more
wiley +1 more source
Estimation of Covid-19 Prevalence from Serology Tests: A Partial Identification Approach [PDF]
We propose a partial identification method for estimating disease prevalence from serology studies. Our data are results from antibody tests in some population sample, where the test parameters, such as the true/false positive rates, are unknown. Our method scans the entire parameter space, and rejects parameter values using the joint data density as ...
arxiv
PepSIRF + QIIME 2: software tools for automated, reproducible analysis of highly-multiplexed serology data [PDF]
PepSIRF is a command-line, module-based open-source software package that facilitates the analysis of data from highly-multiplexed serology assays (e.g., PepSeq or PhIP-Seq). It has nine separate modules in its current release (v1.5.0): demux, info, subjoin, norm, bin, zscore, enrich, link, and deconv.
arxiv
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Reflections on Bayesian inference and Markov chain Monte Carlo
Abstract Bayesian inference and Markov chain Monte Carlo methods are vigorous areas of statistical research. Here we reflect on some recent developments and future directions in these fields. Résumé L'inférence bayésienne et les méthodes de Monte‐Carlo par chaîne de Markov sont des domaines dynamiques de la recherche statistique.
Radu V. Craiu+2 more
wiley +1 more source
Level of Serum Neopterin and Interleukin-6 In Patients with Thyroid Diseases
The purpose of the study was to characterize the immune status in 88 patients (64 women and 24 men) with thyroid diseases and in 36 healthy blood donors as control group.
Kondera-Anasz Zdzislawa, Mertas Anna
doaj +1 more source
Prediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses [PDF]
Human seasonal influenza viruses evolve rapidly, enabling the virus population to evade immunity and re-infect previously infected individuals. Antigenic properties are largely determined by the surface glycoprotein hemagglutinin (HA) and amino acid substitutions at exposed epitope sites in HA mediate loss of recognition by antibodies.
arxiv +1 more source
Abstract Intravenous edaravone is used to treat patients with amyotrophic lateral sclerosis. This randomized, open‐label, two‐way crossover, single‐dose phase 1 study compared the relative bioavailability of a newly developed edaravone oral suspension when administered orally and via a nasogastric tube (NGT) as a model of percutaneous endoscopic ...
Hidetoshi Shimizu+6 more
wiley +1 more source
Background. Discrepancies between histology and serology results for Helicobacter pylori detection could be caused by a variety of factors, including a biopsy sampling error, expertise of the pathologist, natural loss of infection due to advanced atrophy,
Sabine Skrebinska+16 more
doaj +1 more source
Psychiatric manifestations of multiple sclerosis and acute disseminated encephalomyelitis [PDF]
It is unusual for acute disseminated encephalomyelitis and multiple sclerosis to present as purely psychiatric disorders. We report five patients with such demyelinating diseases and symptoms of psychosis, depression or anxiety.
Brinar, Marko+3 more
core +1 more source