Results 161 to 170 of about 24,338 (259)

Clinical Features and Predictors of Hospital Stay in Paediatric Epstein–Barr Virus Infectious Mononucleosis: A Multicentre Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim To describe age‐specific clinical features and identify predictors of length of hospital stay in children and adolescents with primary Epstein–Barr virus (EBV) infectious mononucleosis (IM). Methods This multicentre retrospective cohort study included all children and adolescents aged 0–17 years with a verified primary EBV infection in the
Lasse H. Nyhegn, Sara Yde Steffensen, Sabine Frølich Maarbjerg, Luise Borch, Marianne Kragh Thomsen, Mette Holm   +5 more
wiley   +1 more source

Screen‐Detected Coeliac Disease in a Nationally Representative Cohort: Health Indicators, Long‐Term Outcomes and Mortality

Alimentary Pharmacology &Therapeutics, EarlyView.
In a nationally representative Finnish cohort, screen‐detected coeliac disease was associated with iron deficiency, anaemia, and an atherogenic lipid profile at diagnosis, but long‐term gluten‐free treatment did not adversely affect quality of life, metabolic health, or mortality; supporting a favourable benefit‐harm balance for population‐based ...
Iida Ahonen, Kalle Kurppa, Heini Huhtala, Katri Kaukinen, Laura Kivelä, Juha Taavela   +5 more
wiley   +1 more source

Spatial heterogeneity in exposure to Brucella suis and pathogenic leptospires in feral pigs across New South Wales

Australian Veterinary Journal, EarlyView.
Feral pigs (Sus scrofa) are important reservoirs for zoonotic and livestock pathogens in Australia, but robust information on the spatial distribution of pathogens in pig populations remains limited. We analysed serological data from a systematic, state‐wide surveillance program to investigate spatial heterogeneity in exposure to Brucella suis and ...
AJ Bengsen, S Comte, L Parker, C Brausch, F Silva, M Suann, ME Westman, J Geoghegan, R Powell, DM Forsyth, SR McLeod   +10 more
wiley   +1 more source

Performance of point‐of‐care tests for diagnosing feline immunodeficiency virus infection in captive African lions (Panthera leo)

Australian Veterinary Journal, EarlyView.
Point‐of‐care (PoC) antibody (Ab) testing forms an integral component of feline immunodeficiency virus (FIV) diagnosis in both domestic and non‐domestic felids, with test kits designed for use in domestic cats frequently extrapolated for use in their wild counterparts. The SNAP® FIV/FeLV Combo lateral flow ELISA is commonly used to assign FIV infection
SE Jobbins, ME Westman, K Vinette Herrin, T Meili, R Hofmann‐Lehmann, JM Norris   +5 more
wiley   +1 more source

The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders

Brain Pathology, EarlyView.
Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu, Yoshiki Takai, Naoya Yamazaki, Sarah Brandl, Katharina M. Mair, Thibault Bouderlique, Maria Eleni Kastriti, Igor Adameyko, Romana Höftberger, Markus Reindl, Jan Bauer, Monika Bradl   +11 more
wiley   +1 more source

A defensive symbiont and a plant virus confer direct and discrete phenotypes to a cereal aphid in a context‐dependent manner

Ecological Entomology, EarlyView.
Different BYDV‐PAV isolates exert contrasting effects on aphid fitness, including reproduction and winged production. Different BYDV‐PAV isolates have contrasting effects on aphid dispersal patterns. Aphid feeding behaviour is modulated by the presence of endosymbionts and plant viruses.
Daniel J. Leybourne, Andrea Ceribelli, Sharon E. Zytynska   +2 more
wiley   +1 more source

Attitudes of Dental Students Towards HIV+ Patients: A Multi‐Center Survey Among Italian Universities

European Journal of Dental Education, EarlyView.
ABSTRACT Aims To evaluate the attitudes of Italian dental students towards HIV‐infected patients and explore factors influencing discriminatory behaviour. Methods This observational, multicentric survey analysed responses from dental students across Italian Dental Schools.
Michele Giuliani, Cosimo Rupe, Silvio Abati, Paolo Arduino, Lorenzo Azzi, Elena Bardellini, Giulia Bardini, Lavinia Barone, Selene Barone, Maria Eleonora Bizzoca, Giuseppina Campisi, Claudia Caravetta, Raffaella Castagnola, Marco Cicciù, Maria Contaldo, Francesca Conti, Noemi Coppola, Massimo Cordaro, Elisabetta Cotti, Roberto Di Lenarda, Davide Farronato, Gianfranco Favia, Olga Anna Furchì, Andrea Gabusi, Alessio Gambino, Marco Gargari, Ilaria Giovannacci, Davide Gissi, Amerigo Giudice, Luigi Laino, Gaetano La Mantia, Luisa Limongelli, Lorenzo Lo Muzio, Alessandra Majorana, Mirko Martelli, Marco Mascitti, Michele Davide Mignogna, Pietro Montagna, Pier Francesco Nocini, Romeo Patini, Matteo Pellegrini, Monica Pentenero, Antonio Rapani, Silvana Rizzo, Umberto Romeo, Vincenzo Ronsivalle, Diana Russo, Andrea Santarelli, Francesco Scilla, Rosario Serpico, Francesco Spadari, Gianluca Tenore, Ludovica Vassalli, Paolo Vescovi, Gioele Gioco, Carlo Lajolo   +55 more
wiley   +1 more source

Bringing Gene Therapy Into Real World Clinical Practice

Haemophilia, EarlyView.
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach, Pratima Chowdary, Margareth C. Ozelo   +2 more
wiley   +1 more source

Anti‐Integrin αvβ6 Autoantibodies as Diagnostic and Monitoring Biomarkers for Pediatric‐Onset Primary Sclerosing Cholangitis

Hepatology Research, EarlyView.
Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda, Shuichiro Umetsu, Eitaro Hiejima, Mitsuyoshi Suzuki, Itaru Iwama, Takeshi Kimura, Sonoko Kondo, Ayano Inui, Hiroki Kondou, Tatsuya Okamoto, Takashi Ito, Hiroyuki Shirahase, Kazushi Izawa, Takahiro Yasumi, Takeshi Kuwada, Masahiro Shiokawa, Hiroshi Seno, Junko Takita   +17 more
wiley   +1 more source

A scoping review of the acceptability, feasibility and effectiveness of opt‐out blood‐borne virus (BBV) testing in secondary healthcare settings, in the UK and similar settings, using APEASE criteria

HIV Medicine, EarlyView.
Abstract Background Earlier diagnosis of blood‐borne viruses (BBVs)—HIV, hepatitis B (HBV) and hepatitis C (HCV)—remains a significant public‐health focus. Opt‐out testing in secondary healthcare settings can improve early diagnosis and linkage to care as part of BBV transmission elimination targets.
Becky Metcalfe, Karen J. Maxwell, Kirsten Trayner, Max Wilkinson, Sharon Hutchinson, Claudia Estcourt, Alison J. Rodger   +6 more
wiley   +1 more source