Results 141 to 150 of about 24,338 (259)

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Clinical Characteristics and Treatment Management of Seronegative Myasthenia Gravis: A Systematic Review of the Literature

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Seronegative myasthenia gravis (SNMG) is characterized by the absence of detectable autoantibodies against known MG targets, despite clinical and electrophysiological evidence of a postsynaptic neuromuscular junction disorder. The aim of this systematic review was to better define clinical features, diagnostic clues and treatment outcome of ...
Massimiliano Ugo Verza   +6 more
wiley   +1 more source

IgG Subclass (IgG1‐4) and IgA Autoantibody Profiles Against Muscle‐Specific Kinase in a Greek Cohort

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Muscle‐specific kinase myasthenia gravis (MuSK‐MG) is an autoimmune neuromuscular disorder predominantly mediated by IgG4 autoantibodies disrupting MuSK signaling. The contribution of other isotypes remains incompletely defined. We characterized the serological profile of a Greek cohort of MuSK‐MG patients.
Sofia‐Natsοuko Gkotzamani   +22 more
wiley   +1 more source

Effectiveness and safety of efgartigimod in patients with anti‐NMDAR or anti‐LGI1 encephalitis and its 18F‐DPA714 PET imaging evaluation: A multicenter, single‐arm, prospective, observational real‐world study

open access: yesNeuroprotection, EarlyView.
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng   +12 more
wiley   +1 more source

Toxoplasma gondii seropositivity and substance use in US adults [PDF]

open access: yes, 2018
The intracellular parasite Toxoplasma gondii (Nicolle et Manceaux, 1908) infects humans resulting in acute toxoplasmosis, an infection that in immunocompetent people is typically mild but results in persistent latent toxoplasmosis. In that T.
Gale, Shawn D   +5 more
core  

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

open access: yesRheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues   +6 more
wiley   +1 more source

ASSOCIATION BETWEEN HELICOBACTER PYLORI SEROPOSITIVITY AND HEPATIC ENCEPHALOPATHY

open access: yes, 2020
Objective: The knowledge on Helicobacter pylori (H. pylori) contribution in the pathology of the liver and biliary tract diseases in human is very limited. The aim of this study was to assess the probable association between H.
Ezat Rahimi   +2 more
core  

Frequency of Brucella canis seropositivity in at‐risk dogs referred for veterinary care in the UK

open access: yesVeterinary Record, EarlyView.
Abstract Background Brucella canis is a canine pathogen of zoonotic concern. It is not considered endemic in the UK, with most infections diagnosed in travelled dogs or their offspring. Methods Between March 2021 and December 2022, all dogs with a history of travel outside of the UK or clinical signs compatible with brucellosis referred for veterinary ...
Josh Kennils   +3 more
wiley   +1 more source

Porcine circovirus 2 vaccination timing was not associated with piglets’ serological response

open access: yesVeterinary Record, EarlyView.
Abstract Background The development of immunity in pigs starts in utero, but piglets are born immunologically immature and rely on maternal antibodies. Weaning exposes piglets to multiple stressors, yet vaccination is commonly performed around weaning.
Lea Uotinen   +3 more
wiley   +1 more source

Diffuse Skin Sclerosis in a Patient With Lung Cancer

open access: yes
JEADV Clinical Practice, EarlyView.
Anna‐Sophia Leven   +2 more
wiley   +1 more source

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