Results 1 to 10 of about 66,706 (287)

Brain serotonergic fibers suggest anomalous diffusion-based dropout in artificial neural networks [PDF]

open access: goldFrontiers in Neuroscience, 2022
Random dropout has become a standard regularization technique in artificial neural networks (ANNs), but it is currently unknown whether an analogous mechanism exists in biological neural networks (BioNNs).
Christian Lee   +2 more
doaj   +2 more sources

Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism

open access: goldeLife
Parkinson’s disease (PD) is characterized by motor impairments caused by degeneration of dopamine neurons in the substantia nigra pars compacta. In addition to these symptoms, PD patients often suffer from non-motor comorbidities including sleep and ...
Laura Boi   +5 more
doaj   +2 more sources

Mechanosensitivity of Murine Lung Slowly Adapting Receptors: Minimal Impact of Chemosensory, Serotonergic, and Purinergic Signaling

open access: yesFrontiers in Physiology, 2022
Murine slowly adapting receptors (SARs) within airway smooth muscle provide volume-related feedback; however, their mechanosensitivity and morphology are incompletely characterized.
Nicolle J. Domnik   +3 more
doaj   +1 more source

Involvement of GABAergic and Serotonergic Systems in the Antinociceptive Effect of Jegosaponin A Isolated from Styrax japonicus

open access: yesMolecules, 2023
The antinociceptive activity of the flower extracts of Styrax japonicus was confirmed in our previous study. However, the key compound for analgesia has not been distinguished, and the corresponding mechanism is obscure.
Lei He   +4 more
doaj   +1 more source

Methyleugenol Has an Antidepressant Effect in a Neuroendocrine Model: In Silico and In Vivo Evidence

open access: yesPharmaceuticals, 2023
Major depressive disorder is a severe mood disorder characterized by different emotions and feelings. This study investigated the antidepressant activity of the phenylpropanoid methyleugenol (ME) in adult female mice exposed to a stress model induced by ...
Mayara Cecile Nascimento Oliveira   +13 more
doaj   +1 more source

A Comprehensive Review of the Current Status of the Cellular Neurobiology of Psychedelics

open access: yesBiology, 2023
Psychedelic substances have gained significant attention in recent years for their potential therapeutic effects on various psychiatric disorders. This review delves into the intricate cellular neurobiology of psychedelics, emphasizing their potential ...
Blerida Banushi, Vince Polito
doaj   +1 more source

High-resolution spatiotemporal analysis of single serotonergic axons in an in vitro system

open access: yesFrontiers in Neuroscience, 2022
Vertebrate brains have a dual structure, composed of (i) axons that can be well-captured with graph-theoretical methods and (ii) axons that form a dense matrix in which neurons with precise connections operate.
Melissa Hingorani   +3 more
doaj   +1 more source

Brain serotonergic circuitries [PDF]

open access: yesDialogues in Clinical Neuroscience, 2010
Brain serotonergic circuitries interact with other neurotransmitter systems on a multitude of different molecular levels. In humans, as in other mammalian species, serotonin (5-HT) plays a modulatory role in almost every physiological function.
Charnay, Yves, Leger, Lucienne
openaire   +3 more sources

The modulation effects of repeated transcutaneous auricular vagus nerve stimulation on the functional connectivity of key brainstem regions along the vagus nerve pathway in migraine patients

open access: yesFrontiers in Molecular Neuroscience, 2023
BackgroundPrevious studies have shown a significant response to acute transcutaneous vagus nerve stimulation (taVNS) in regions of the vagus nerve pathway, including the nucleus tractus solitarius (NTS), raphe nucleus (RN) and locus coeruleus (LC) in ...
Yiting Huang   +10 more
doaj   +1 more source

A single dose of noradrenergic/serotonergic reuptake inhibitors combined with an antimuscarinic does not improve obstructive sleep apnoea severity

open access: yesPhysiological Reports, 2022
Previous trials have demonstrated that the combination of noradrenergic reuptake inhibitors with an antimuscarinic can substantially reduce the apnoea‐hypopnoea index (AHI) and improve airway collapsibility in patients with obstructive sleep apnoea (OSA).
Luke D. J. Thomson   +9 more
doaj   +1 more source

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