Results 11 to 20 of about 66,706 (287)

Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation

Frontiers in Cell and Developmental Biology, 2021
The serotonergic system of mammals innervates virtually all the central nervous system and regulates a broad spectrum of behavioral and physiological functions.
Candela Barettino, Álvaro Ballesteros-Gonzalez, Andrés Aylón, Xavier Soler-Sanchis, Leticia Ortí, Selene Díaz, Isabel Reillo, Francisco García-García, Francisco José Iborra, Cary Lai, Nathalie Dehorter, Xavier Leinekugel, Nuria Flames, Isabel Del Pino   +13 more
doaj   +1 more source

Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons

Frontiers in Neural Circuits, 2019
Dopaminergic and serotonergic neurons modulate and control processes ranging from reward signaling to regulation of motor outputs. Further, dysfunction of these neurons is involved in both degenerative and psychiatric disorders.
Alexandra Krol, Violeta G. Lopez-Huerta, Violeta G. Lopez-Huerta, Violeta G. Lopez-Huerta, Taylor E. C. Corey, Karl Deisseroth, Karl Deisseroth, Karl Deisseroth, Jonathan T. Ting, Jonathan T. Ting, Guoping Feng, Guoping Feng   +11 more
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Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn

eLife, 2023
Spinally projecting serotonergic neurons play a key role in controlling pain sensitivity and can either increase or decrease nociception depending on physiological context.
Robert Philip Ganley, Marilia Magalhaes de Sousa, Kira Werder, Tugce Öztürk, Raquel Mendes, Matteo Ranucci, Hendrik Wildner, Hanns Ulrich Zeilhofer   +7 more
doaj   +1 more source

Dopaminergic and serotonergic drug use: a nationwide register-based study of over 1,300,000 older people. [PDF]

PLoS ONE, 2011
OBJECTIVE: To investigate the use of dopaminergic and serotonergic drugs in elderly people. METHODS: We analyzed data on age, sex and dispensed drugs for individuals aged ≥65 years registered in the Swedish Prescribed Drug Register from July to September
Kristina Johnell, Håkan Fischer
doaj   +1 more source

Characterization of the Sexually Dimorphic fruitless Neurons That Regulate Copulation Duration

Frontiers in Physiology, 2018
Male courtship in Drosophila melanogaster is a sexually dimorphic innate behavior that is hardwired in the nervous system. Understanding the neural mechanism of courtship behavior requires the anatomical and functional characterization of all the neurons
Shreyas Jois, Yick Bun Chan, Maria Paz Fernandez, Adelaine Kwun-Wai Leung   +3 more
doaj   +1 more source

Synaptic activity in serotonergic neurons is required for air-puff stimulated flight in Drosophila melanogaster. [PDF]

PLoS ONE, 2012
BACKGROUND: Flight is an integral component of many complex behavioral patterns in insects. The giant fiber circuit has been well studied in several insects including Drosophila.
Sufia Sadaf, Serge Birman, Gaiti Hasan
doaj   +1 more source

Investigation of the Serotonergic Activity and the Serotonin Content in Serum and Platelet, and the Possible Role of the Serotonin Transporter in Patients with Depression

Behavioral Sciences, 2022
According to the monoamine hypothesis, the development of depression is associated with dysfunctions of the serotonergic system. Alterations in the serotonin transporter gene (5-HTTLPR), the serotonergic activity in the brain, and the content of ...
Jasmin Obermanns, Vera Flasbeck, Saskia Steinmann, Georg Juckel, Barbara Emons   +4 more
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Interactions Between the Serotonergic and Other Neurotransmitter Systems in the Basal Ganglia: Role in Parkinson’s Disease and Adverse Effects of L-DOPA

Frontiers in Neuroanatomy, 2020
Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. However, other non-dopaminergic neuronal systems such as the serotonergic system are also involved.
Ana Muñoz, Ana Muñoz, Andrea Lopez-Lopez, Andrea Lopez-Lopez, Carmen M. Labandeira, Jose L. Labandeira-Garcia, Jose L. Labandeira-Garcia   +6 more
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Mirtazapine for the Treatment of Chronic Pruritus

Medicines, 2019
Background: Chronic pruritus is a debilitating condition associated with a wide range of dermatologic, systemic and psychogenic etiologies. In patients with chronic pruritus that is refractory to conventional therapy, symptoms can significantly decrease ...
Raveena Khanna, Emily Boozalis, Micah Belzberg, John G. Zampella, Shawn G. Kwatra   +4 more
doaj   +1 more source

An experimental platform for stochastic analyses of single serotonergic fibers in the mouse brain

Frontiers in Neuroscience, 2023
The self-organization of the serotonergic matrix, a massive axon meshwork in all vertebrate brains, is driven by the structural and dynamical properties of its constitutive elements.
Kasie C. Mays, Justin H. Haiman, Skirmantas Janušonis   +2 more
doaj   +1 more source