Symptoms of exhibitionism that regress with bupropion: A case report
Frontiers in Psychiatry, 2023 Exhibitionistic Disorder, one of the paraphilic disorders, is a disease with an unknown etiology and causes significant distress and loss of function in the patient's life.
Sefa Vayısoğlu
doaj +1 more source
Biophysical properties and computational modeling of calcium spikes in serotonergic neurons of the dorsal raphe nucleus [PDF]
arXiv, 2012 Serotonergic neurons of the dorsal raphe nuclei, with their extensive innervation of nearly the whole brain have important modulatory effects on many cognitive and physiological processes. They play important roles in clinical depression and other psychiatric disorders. In order to quantify the effects of serotonergic transmission on target cells it is
arxiv
Dampening of Serotonergic System through 5HT1A Receptors is a Promising Target for Treatment of Levodopa Induced Motor Problems [PDF]
Advanced Pharmaceutical Bulletin, 2013 During long-term treatment with Levodopa, majority of patients with Parkinson's disease experience some abnormal motor problems including of Levodopa induced dyskinesia (LID) and wearing off.
Javad Mahmoudi +3 more
doaj +1 more source
Characterization of Induced Pluripotent Stem Cell-derived Human Serotonergic Neurons
Frontiers in Cellular Neuroscience, 2017 In the brain, the serotonergic neurons located in the raphe nucleus are the unique resource of the neurotransmitter serotonin, which plays a pivotal role in the regulation of brain development and functions. Dysfunction of the serotonin system is present
Lining Cao +6 more
doaj +1 more source
Biology Open, 2019 In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute a prominent population. In contrast to the hindbrain serotonergic neurons, little is known about the development and function ...
Isabel Reuter +5 more
doaj +1 more source
Properties of IA in a serotonergic neuron of the dorsal raphe nucleus [PDF]
arXiv, 2011 Voltage clamp data were analyzed in order to characterize the properties of the fast potassium transient current IA for a serotonergic neuron of the rat dorsal raphe nucleus (DRN). We obtain maximal conductance, time constants of activation and inactivation, and the steady state activation and inactivation functions, as Boltzmann curves, defined by ...
arxiv
Scientifica, 2016 Background. Surgery for GI dysmotility is limited to those with severe refractory disease. Though effective, use of serotonergic promotility drugs has been restricted in Canada due to adverse events.
Biniam Kidane +3 more
doaj +1 more source
Simplified models of pacemaker spiking in raphe and locus coeruleus neurons [PDF]
arXiv, 2015 Many central neurons, and in particular certain brainstem aminergic neurons exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz. A large number of ion channel types contribute to such spiking so that accurate modeling of spike generation leads to the requirement of solving very large systems of differential equations ...
arxiv
Clinical Relevance of Pharmacogenetics in Serotonin Syndrome
Case Reports in Psychiatry, 2020 Serotonin syndrome is a predictable life-threatening condition that is caused by serotonergic stimulation of the central and peripheral nervous systems.
Dehuti Pandya +2 more
doaj +1 more source
Depressive patients are more impulsive and inconsistent in intertemporal choice behavior for monetary gain and loss than healthy subjects- an analysis based on Tsallis' statistics [PDF]
Neuro Endocrinol Lett. 2008, 29(3):351-358, 2011 Depression has been associated with impaired neural processing of reward and punishment. However, to date, little is known regarding the relationship between depression and intertemporal choice for gain and loss. We compared impulsivity and inconsistency in intertemporal choice for monetary gain and loss (quantified with parameters in the q-exponential
arxiv