Results 51 to 60 of about 2,360 (67)

Neuromodulated Patience for Robot and Self-Driving Vehicle Navigation [PDF]

open access: yesarXiv, 2019
Robots and self-driving vehicles face a number of challenges when navigating through real environments. Successful navigation in dynamic environments requires prioritizing subtasks and monitoring resources. Animals are under similar constraints. It has been shown that the neuromodulator serotonin regulates impulsiveness and patience in animals.
arxiv  

Serotonergic neurons control cortical neuronal intracellular energy dynamics by modulating astrocyte-neuron lactate shuttle

open access: yesiScience, 2023
Summary: The central serotonergic system has multiple roles in animal physiology and behavior, including sleep-wake control. However, its function in controlling brain energy metabolism according to the state of animals remains undetermined.
Akiyo Natsubori   +12 more
doaj  

Serotonergic neurons signal reward and punishment on multiple timescales

open access: yeseLife, 2015
Serotonin's function in the brain is unclear. One challenge in testing the numerous hypotheses about serotonin's function has been observing the activity of identified serotonergic neurons in animals engaged in behavioral tasks.
Jeremiah Y Cohen   +2 more
doaj   +1 more source

Serotonin Syndrome in the Setting of Lamotrigine, Aripiprazole, and Cocaine Use

open access: yesCase Reports in Medicine, 2015
Serotonin syndrome is a potentially life-threatening condition associated with increased serotonergic activity in the central nervous system. It is classically associated with the simultaneous administration of two serotonergic agents, but it can occur ...
Anupam Kotwal, Sarah L. Cutrona
doaj   +1 more source

Computational modeling of spike generation in serotonergic neurons of the dorsal raphe nucleu [PDF]

open access: yesarXiv, 2012
We consider here a single-compartment model of these neurons which is capable of describing many of the known features of spike generation, particularly the slow rhythmic pacemaking activity often observed in these cells in a variety of species. Included in the model are ten kinds of voltage dependent ion channels as well as calcium-dependent potassium
arxiv  

Analysis of pacemaker activity in a two-component model of some brainstem neurons [PDF]

open access: yesarXiv, 2017
Serotonergic, noradrenergic and dopaminergic brainstem (including midbrain) neurons, often exhibit spontaneous and fairly regular spiking with frequencies of order a few Hz, though dopaminergic and noradrenergic neurons only exhibit such pacemaker-type activity in vitro or in vivo under special conditions.
arxiv  

Control of Functional Connectivity in Cerebral Cortex by Basal Ganglia Mediated Synchronization [PDF]

open access: yesarXiv, 2017
Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. More recently, they have been identified not only in the cerebral cortex and thalamus, but pervasively in the healthy basal ganglia.
arxiv  

Synthetic Data for Discriminating Serotonergic Neurons using Convolutional Neural Networks [PDF]

open access: yesarXiv
Serotonergic neurons in the raphe nuclei exhibit diverse electrophysiological properties and functional roles, yet conventional identification methods rely on restrictive criteria that likely overlook atypical serotonergic cells. The use of convolutional neural network (CNN) for comprehensive classification of both typical and atypical serotonergic ...
arxiv  

The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord

open access: yesScientific Reports, 2017
Descending connections from brainstem nuclei are known to exert powerful control of spinal nociception and pain behaviours in adult mammals. Here we present evidence that descending serotonergic fibres not only inhibit nociceptive activity, but also ...
F. Schwaller   +2 more
doaj   +1 more source

Adenoviral vectors for highly selective gene expression in central serotonergic neurons reveal quantal characteristics of serotonin release in the rat brain

open access: yesBMC Biotechnology, 2009
Background 5-hydroxytryptamine (5 HT, serotonin) is one of the key neuromodulators in mammalian brain, but many fundamental properties of serotonergic neurones and 5 HT release remain unknown.
Teschemacher Anja G   +4 more
doaj   +1 more source

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