Results 61 to 70 of about 66,706 (287)
Scientifica, 2016 Background. Surgery for GI dysmotility is limited to those with severe refractory disease. Though effective, use of serotonergic promotility drugs has been restricted in Canada due to adverse events.
Biniam Kidane +3 more
doaj +1 more source
Neurobiological correlates of obsessive‐compulsive disorder (OCD): A narrative review
Ibrain, EarlyView.Obsessive‐compulsive disorder (OCD) is a common and disabling, as well as underdiagnosed, neuropsychiatric condition characterized by involuntary and unwanted obsessions and/or compulsions often accompanied by states of severe anxiety, distress and shame, as well as other comorbid disorders. Despite the extensive literature available to date, only some
Giulio Perrotta, Anna Sara Liberati
wiley +1 more source
Enteric serotonergic neurones … finally!
The Journal of Physiology, 2009 The involvement of serotonin (5-HT) in gastrointestinal (GI) physiology was recognized even before its structure had been discovered or anything was known about its role in the central nervous system. In 1937, Vittorio Erspamer extracted a factor, derived from the enterochromaffin (EC) cells of the GI epithelium, which he identified as an amine and ...
openaire +3 more sources
Psychosocial and menstrual correlates of premenstrual disorders: A community‐based study
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To assess the background, psychosocial, and menstrual factors associated with premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in a community‐based cohort. Methods A prospective cohort study was conducted using data from users of a menstrual tracking application.
Shiori Itoi +6 more
wiley +1 more source
iMetaOmics, EarlyView.This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang +7 more
wiley +1 more source
iMetaOmics, EarlyView.Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley +1 more source
Biology Open, 2019 In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute a prominent population. In contrast to the hindbrain serotonergic neurons, little is known about the development and function ...
Isabel Reuter +5 more
doaj +1 more source
Clinical Relevance of Pharmacogenetics in Serotonin Syndrome
Case Reports in Psychiatry, 2020 Serotonin syndrome is a predictable life-threatening condition that is caused by serotonergic stimulation of the central and peripheral nervous systems.
Dehuti Pandya +2 more
doaj +1 more source
Serotonergic dysfunction and aggression control [PDF]
Psychological Medicine, 1991 In the early 1970s we reported the occurrence of diminished accumulation of 5-hydroxyindoleacetic acid (5-HIAA) in cerebrospinal fluid (CSF) after probenecid administration in depression (van Praag et al. 1970; van Praag and Korf 1971). Lowered baseline and postprobenecid 5-HIAA levels in CSF are an indication of diminished metabolism of the mother ...
openaire +2 more sources
iNew Medicine, EarlyView.In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu +10 more
wiley +1 more source