Results 81 to 90 of about 66,706 (287)

The developmental emergence of differential brainstem serotonergic control of the sensory spinal cord

open access: yesScientific Reports, 2017
Descending connections from brainstem nuclei are known to exert powerful control of spinal nociception and pain behaviours in adult mammals. Here we present evidence that descending serotonergic fibres not only inhibit nociceptive activity, but also ...
F. Schwaller   +2 more
doaj   +1 more source

Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues

open access: yesSmall Methods, EarlyView.
This review summarizes recent advances in nongenetic optoelectronic technologies for the modulation of excitable biotissues, covering material selection, device design, and working principles, as well as characterization methods. Representative applications in in vitro and in vivo models of the cardiac, central, and peripheral nervous systems are ...
Qi Wang, Jinghua Li
wiley   +1 more source

Inducible gene manipulations in serotonergic neurons

open access: yesFrontiers in Molecular Neuroscience, 2009
An impairment of the serotonergic (5-HT) system has been implicated in the etiology of many neuropsychiatric disorders. Despite the considerable genetic evidence, the exact molecular and pathophysiological mechanisms underlying this dysfunction remain ...
Tillmann Weber   +6 more
doaj   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa   +9 more
wiley   +1 more source

Comprehensive Evaluation of Bisphenol A Toxicity Reveals Neurobehavioral, Metabolic, and Reproductive Impairments in Girardia tigrina

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a common industrial chemical used in plastics and consumer products, is increasingly detected in aquatic environments, raising serious concerns about its potential ecological impacts. This study evaluated the sublethal and acute toxic effects of BPA on the freshwater planarian Girardia tigrina, a recognized model for ...
Raquel de Jesus Selestrino   +2 more
wiley   +1 more source

Spinal 5-HT7 Receptors Play an Important Role in the Antinociceptive and Antihyperalgesic Effects of Tramadol and Its Metabolite, O-Desmethyltramadol, via  Activation of Descending Serotonergic Pathways [PDF]

open access: bronze, 2010
Ömer Yanarateş   +9 more
openalex   +1 more source

Factors Associated With Non‐Vasomotor Menopause Symptoms Experienced by 7285 Women: A UK‐Wide National Survey

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate the factors associated with non‐vasomotor menopause symptoms among women in the UK, focusing on the perceived importance of specific symptoms and their association with demographic and treatment‐related factors. Design A cross‐sectional online survey.
Rhianna Davies   +12 more
wiley   +1 more source

Prenatal Environmental Hypoxia Enhances Adult Hypoxia Tolerance in Brandt's Voles (Lasiopodomys brandtii): Behavioral and Transcriptomic Insights

open access: yesIntegrative Zoology, EarlyView.
Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li   +5 more
wiley   +1 more source

Clinical guidelines highlight for the hospitalist: Management of cyclic vomiting syndrome in children

open access: yes
Journal of Hospital Medicine, EarlyView.
Yamileth N. Hernandez, Hannah M. Gardner
wiley   +1 more source

Home - About - Disclaimer - Privacy