Results 51 to 60 of about 25,888 (267)

A brief review of the pharmacology of amitriptyline and clinical outcomes in treating fibromyalgia [PDF]

open access: yes, 2017
Fibromyalgia is a complex chronic condition characterized by pain, physical fatigue, sleep disorder and cognitive impairment. Evidence-based guidelines recommend antidepressants as treatments of fibromyalgia where tricyclics are often considered to have ...
Azad   +12 more
core   +2 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Late-life depression : issues for the general practitioner [PDF]

open access: yes, 2018
Late-life depression (LLD) is both a prevalent and life-threatening disorder, affecting up to 13.3% of the elderly population. LLD can be difficult to identify because patients mainly consult their general practitioner (GP) for somatic complaints ...
Declercq, Tom   +4 more
core   +1 more source

Parkinsonism associated with a serotonin and noradrenaline reuptake inhibitor, milnacipran [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 2003
Milnacipran is a new class of antidepressant, a dual serotonin (5-HT) and noradrenaline (norepinephrine) reuptake inhibitor (SNRI).1 It shows no affinity for neurotransmitter receptors.1 The use of selective serotonin reuptake inhibitor (SSRI) has been associated with the occurrence and worsening of parkinsonism.2,3 However, SNRI induced parkinsonism ...
openaire   +1 more source

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung   +21 more
wiley   +1 more source

Comparative Safety of Pharmacologic Treatments for Persistent Depressive Disorder: A Systematic Review and Network Meta-Analysis.

open access: yesPLoS ONE, 2016
We aimed to compare the safety of antidepressants for the treatment of persistent depressive disorder (PDD) with each other and with placebo. We conducted a systematic electronic search and included randomized controlled trials that investigated ...
Ramona Meister   +6 more
doaj   +1 more source

Pharmacological profile of prescriptions containing antidepressants

open access: yesJournal of Marine Medical Society, 2021
Background: The prescription of antidepressants is increasing due to the increasing incidence of depression and the use of antidepressants in other indications.
Prafull Mohan   +3 more
doaj   +1 more source

The Role of the Sympathetic Nervous System in the Hypothermic Effect of d-Fenfluramine [PDF]

open access: yes, 2002
Experiments in this dissertation were conducted to characterize the effects of d-fenfluramine on body temperature and the mechanisms by which d-fenfluramine alter body temperature.
Subramanian, Srividya
core   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi   +3 more
wiley   +1 more source

Unveiling the efficacy of paroxetine and gabapentin in ulcerative colitis patients in remission with co-existing IBS-like symptoms: a single-blinded randomized clinical trial

open access: yesFrontiers in Medicine
IntroductionThis clinical trial is designed to explore the efficacy of paroxetine and gabapentin in alleviating functional gastrointestinal symptoms, anxiety, depression, and quality of life in patients with ulcerative colitis during the remission stage ...
Farahnaz Safaei   +4 more
doaj   +1 more source

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