Results 31 to 40 of about 25,888 (267)

Influence of mirtazapine on salivary cortisol in depressed patients [PDF]

open access: yes, 2003
Unlike other antidepressants, mirtazapine does not inhibit the reuptake of norepinephrine or serotonin but acts as an antagonist at presynaptic alpha(2)-receptors, at postsynaptic 5-HT2 and 5-HT3 receptors, and at histaminergic H1 receptors. Furthermore,
Baghai, Thomas C.   +3 more
core   +1 more source

GENetic and clinical Predictors Of treatment response in Depression: the GenPod randomised trial protocol

open access: yesTrials, 2008
Background The most effective pharmacological treatments for depression inhibit the transporters that reuptake serotonin (Selective Serotonin Reuptake Inhibitors – SSRIs) and noradrenaline (Noradrenaline Reuptake Inhibitors – NaRIs) into the presynaptic ...
O'Donovan Michael   +10 more
doaj   +1 more source

Clinically important drug interactions with opioid and non-opioid analgesics [PDF]

open access: yesArhiv za farmaciju, 2018
Patients often seek advise from doctors and pharmacists about pain treatment. Opioid and non-opioid analgesics are the most commonly used drugs in the treatment of pain, but they have potential for pharmacodynamic and pharmacokinetic drug-drug ...
Vezmar-Kovačević Sandra   +4 more
doaj   +1 more source

Selective Serotonin Reuptake Inhibitors and Clozapine: Clinically Relevant Interactions and Considerations

open access: yesNeurology International, 2021
The monoamine hypothesis of depression attributes the symptoms of major depressive disorders to imbalances of serotonin, noradrenaline, and dopamine in the limbic areas of the brain.
Amber N. Edinoff   +7 more
doaj   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

open access: yes, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R.   +2 more
core   +1 more source

Antidepressants induce toxicity in human placental BeWo cells

open access: yesCurrent Research in Toxicology, 2022
Selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and noradrenergic and specific serotonergic antidepressants (NaSSAs) are broadly used for the treatment of depression. Depression is one of the most
Tomohiro Nabekura   +4 more
doaj   +1 more source

Venlafaxine-induced acute dystonia: a case report [PDF]

open access: yesDüşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2015
Although mechanisms underlying neuroleptic-induced extrapyramidal symptoms have been well researched, extrapyramidal symptoms associated with antidepressants are understudied. Research conducted to date is more concerned with selective serotonin reuptake
ipek sonmez, ferdi kosger
doaj  

Treatment response to valproate in case with generalized anxiety disorder resistant to antidepressants

open access: yesPsychiatry and Clinical Psychopharmacology, 2017
Objective: Pharmacological treatment of anxiety disorders is an active research field and Selective Serotonin Reuptake Inhibitors (SSRIs) are considered to be the first line of drugs in this treatment. In cases resistant to SSRI, in addition to serotonin-
Sefa Vayısoğlu
doaj   +1 more source

Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.

open access: yesPLoS Medicine, 2012
BackgroundIt has been suggested that outcomes of antidepressant treatment for major depressive disorder could be significantly improved if treatment choice is informed by genetic data.
Katherine E Tansey   +29 more
doaj   +1 more source

Citalopram plus low-dose pipamperone versus citalopram plus placebo in patients with major depressive disorder: an 8-week, double-blind, randomized study on magnitude and timing of clinical response [PDF]

open access: yes, 2011
Background: Selective serotonin reuptake inhibitors take several weeks to achieve their full antidepressant effects. Post-synaptic 5-HT<sub>2A</sub> receptor activation is thought to be involved in this delayed therapeutic effect ...
A. F. Schatzberg   +14 more
core   +1 more source

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