Results 1 to 10 of about 748,112 (249)

Neuropharmacological classification of antidepressant agents based on their mechanisms of action

Archives of Medicine and Health Sciences, 2018
The currently available clinical antidepressants can be classified into 13 different classes based on their mechanisms of action. These basic pharmacological concepts thoroughly elucidate and unravel the therapeutic actions and side effects of the wide ...
Olumuyiwa John Fasipe
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Effect of paroxetine on intestinal motility in the presence of ondansetron

Pakistan Journal of Pharmaceutical Sciences, 2020
Chemotherapy, radiotherapy, surgery and depression are the conditions that run in parallel fashions. All these conditions cause the release of an increased amount of serotonin in the body.
Ayesha Afzal, Ammara Khan, Asma Khan, Rashida Farooqi, Bushra Tayyaba Khan, Iffat Ara   +5 more
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Antipsychotic-induced bone loss: the role of dopamine, serotonin and adrenergic receptor signalling

Frontiers in Cell and Developmental Biology, 2023
Antipsychotics are commonly used in treating psychiatric disorders. These medications primarily target dopamine the serotonin receptors, they have some affinity to adrenergic, histamine, glutamate and muscarinic receptors. There is clinical evidence that
D. Kavindi Weerasinghe, Jason M. Hodge, Jason M. Hodge, Julie A. Pasco, Julie A. Pasco, Julie A. Pasco, Rasika M. Samarasinghe, Behnaz Azimi Manavi, Lana J. Williams, Lana J. Williams   +9 more
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Function and distribution of 5-HT2 receptors in the honeybee (Apis mellifera). [PDF]

PLoS ONE, 2013
BACKGROUND: Serotonin plays a pivotal role in regulating and modulating physiological and behavioral processes in both vertebrates and invertebrates. In the honeybee (Apis mellifera), serotonin has been implicated in division of labor, visual processing,
Markus Thamm, Daniel Rolke, Nadine Jordan, Sabine Balfanz, Christian Schiffer, Arnd Baumann, Wolfgang Blenau   +6 more
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Therapeutic Potential of 5-HT2C Receptor Ligands

The Scientific World Journal, 2010
Serotonin 2C receptors are G protein-coupled receptors expressed by GABAergic, glutamatergic, and dopaminergic neurons. Anatomically, they are present in various brain regions, including cortical areas, hippocampus, ventral midbrain, striatum, nucleus ...
Nanna H. Jensen, Thomas I. Cremers, Florence Sotty   +2 more
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The role of 5-HT receptors in depression

Molecular Brain, 2017
Depression is a polygenic and highly complex psychiatric disorder that remains a major burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are some of the most commonly prescribed drugs worldwide.
Christine N. Yohn, Mark M. Gergues, Benjamin Adam Samuels   +2 more
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Role of 5-HT7 receptors in the immune system in health and disease

Molecular Medicine, 2019
In mammalians, serotonin (5-HT) has critical roles in the central nervous system (CNS), including mood stability, pain tolerance, or sleep patterns.
Alejandro Quintero-Villegas, Sergio Iván Valdés-Ferrer   +1 more
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5-HTP inhibits eosinophilia via intracellular endothelial 5-HTRs; SNPs in 5-HTRs associate with asthmatic lung function

Frontiers in Allergy
BackgroundPrevious research showed that 5-hydroxytryptophan (5HTP), a metabolic precursor of serotonin, reduces allergic lung inflammation by inhibiting eosinophil migration across endothelial monolayers.ObjectiveIt is unknown if serotonin receptors are ...
Matthew T. Walker, Jeffrey C. Bloodworth, Jeffrey C. Bloodworth, Timothy S. Kountz, Samantha L. McCarty, Jeremy E. Green, Ryan P. Ferrie, Jackson A. Campbell, Samantha H. Averill, Kenneth B. Beckman, Leslie C. Grammer, Celeste Eng, Pedro C. Avila, Harold J. Farber, William Rodriguez-Cintron, Jose R. Rodriguez-Santana, Denise Serebrisky, Shannon M. Thyne, Max A. Seibold, Max A. Seibold, Esteban G. Burchard, Rajesh Kumar, Rajesh Kumar, Joan M. Cook-Mills, Joan M. Cook-Mills, Joan M. Cook-Mills   +25 more
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Expression Changes of Serotonin Receptor Gene Subtype 5HT3a in Peripheral Blood Mononuclear Cells from Schizophrenic Patients Treated with Haloperidol and Olanzapin

Iranian Journal of Allergy, Asthma and Immunology, 2009
Serotonin receptors are involved in pathophysiology of schizophrenia and may mediate other neurotransmitter effects. We investigated serotonin receptors gene expression in peripheral blood mononuclear cells (PBMC) of naïve schizophrenic patients, before
Gholam Reza Shariati, Ghasem Ahangari, Arash Hossein-nezhad, Seyed Mohammad Asadi , Farzaneh Pooyafard, Hamid Reza Ahmadkhaniha   +5 more
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Expression of serotonin 2A, 2C, 6 and 7 receptor and IL-6 mRNA in experimental toxoplasmic encephalitis in mice

Heliyon, 2019
The neurotropic pathogen Toxoplasma gondii infects about one-third of the human population. Both acute and chronic (latent or life-long) forms of toxoplasmosis are associated with specific neurologic and neuropsychiatric symptoms.
Hasan Tarik Atmaca
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