Results 1 to 10 of about 1,525,501 (301)
Oligonucleotide‐induced alternative splicing of serotonin 2C receptor reduces food intake
EMBO Molecular Medicine, 2016 The serotonin 2C receptor regulates food uptake, and its activity is regulated by alternative pre‐mRNA splicing. Alternative exon skipping is predicted to generate a truncated receptor protein isoform, whose existence was confirmed with a new antiserum ...
Zhaiyi Zhang +6 more
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Neuropharmacological classification of antidepressant agents based on their mechanisms of action
Archives of Medicine and Health Sciences, 2018 The currently available clinical antidepressants can be classified into 13 different classes based on their mechanisms of action. These basic pharmacological concepts thoroughly elucidate and unravel the therapeutic actions and side effects of the wide ...
Olumuyiwa John Fasipe
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Serotonin Type 6 and 7 Receptors as a Novel Therapeutic Target for the Treatment of Schizophrenia
Neuropsychiatric Disease and Treatment, 2020 Etsay Weldekidan Tsegay,1 Desalegn Getnet Demise,1 Nigus Alemu Hailu,2 Zenawi Hagos Gufue3 1Department of Pharmacy, College of Medicine and Health Sciences, Adigrat University, Adigrat, Tigray, Ethiopia; 2Department of Biomedical Science, College of ...
Tsegay EW, Demise DG, Hailu NA, Gufue ZH
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TrpC5 Mediates Acute Leptin and Serotonin Effects via Pomc Neurons
Cell Reports, 2017 The molecular mechanisms underlying acute leptin and serotonin 2C receptor-induced hypophagia remain unclear. Here, we show that neuronal and pro-opiomelanocortin (Pomc)-specific loss of transient receptor potential cation 5 (TrpC5) subunits is ...
Yong Gao +15 more
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The Effects of Serotonin in Immune Cells
Frontiers in Cardiovascular Medicine, 2017 Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a peripheral hormone. Most of the body’s serotonin is circulating in the bloodstream, transported by blood platelets and is released upon activation.
Nadine Herr +2 more
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Taiwanese Journal of Obstetrics & Gynecology, 2015 Objective: Sleep deprivation (SD) leads to the disturbance of the estrous cycle. Serotonin, the levels of which increase with SD, has been shown to inhibit luteinizing hormone production and the receptor has been found in the follicles.
Chueh-Ko Yang +4 more
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Nature CommunicationsThe nervous system flexibly processes information under different conditions. To do this, neural networks frequently rely on uniform expression of modulatory receptors by distinct classes of neurons to fine tune the computations supported by each ...
Julius Jonaitis +13 more
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Frontiers in Neural Circuits, 2014 To better understand serotonin function in the primate brain, we examined the mRNA expression patterns of all the 13 members of the serotonin receptor (5HTR) family, by in situ hybridization and the distribution of serotonergic terminations by serotonin ...
Rammohan eShukla +2 more
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From behavioral context to receptors: serotonergic modulatory pathways in the IC
Frontiers in Neural Circuits, 2012 In addition to ascending, descending, and lateral auditory projections, inputs extrinsic to the auditory system also influence neural processing in the inferior colliculus.
Laura M Hurley, Megan R Sullivan
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The emerging role of serotonin in liver regeneration
Swiss Medical Weekly, 2012 Serotonin has a multifunctional role in many different organs serving either as a neurotransmitter in the central nervous system or a paracrine factor in the gastrointestinal tract.
George K Papadimas +5 more
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