Results 21 to 30 of about 1,423,567 (298)

The effects of glycogen synthase kinase-3beta in serotonin neurons. [PDF]

open access: yesPLoS ONE, 2012
Glycogen synthase kinase-3 (GSK3) is a constitutively active protein kinase in brain. Increasing evidence has shown that GSK3 acts as a modulator in the serotonin neurotransmission system, including direct interaction with serotonin 1B (5-HT1B) receptors
Wenjun Zhou   +9 more
doaj   +1 more source

Efficacy of serotonin receptor agonists in the treatment of functional dyspepsia: a meta-analysis

open access: yesArchives of Medical Science, 2018
Introduction Functional dyspepsia (FD) is typically treated with serotonin receptor (5-HT) agonists such as cisapride, mosapride, tegaserod and tandospirone citrate.
Man Jin   +5 more
doaj   +1 more source

Endophenotypes and serotonergic polymorphisms associated with treatment response in obsessive-compulsive disorder

open access: yesClinics, 2012
OBJECTIVES: Approximately 40-60% of obsessive-compulsive disorder patients are nonresponsive to serotonin reuptake inhibitors. Genetic markers associated with treatment response remain largely unknown.
Fábio M. Corregiari   +3 more
doaj   +1 more source

5-hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to Its subsequent release [PDF]

open access: yes, 2014
The serotonergic synapse is dynamically regulated by serotonin (5-hydroxytryptamine (5-HT)) with elevated levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, including the 5-HT type-3 (5-HT3) receptors.
Moffat, Christopher   +5 more
core   +1 more source

The Serotonin Receptor Subtype 5b Specifically Interacts with Serotonin Receptor Subtype 1A

open access: yesFrontiers in Molecular Neuroscience, 2017
Previously, we described the dysregulation of serotonin (5-HT) receptor subtype 5b (5-ht5b) in a mouse model of Rett syndrome (RTT). 5-ht5b has not been extensively studied, so we set out to characterize it in more detail.
Sabine Niebert   +7 more
doaj   +1 more source

The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster

open access: yesFrontiers in Aging, 2022
The conserved neurotransmitter serotonin has been shown to be an important modulator of lifespan in specific nutritional contexts; however, it remained unclear how serotonin signaling influences lifespan under normal conditions.
Allyson S. Munneke   +6 more
doaj   +1 more source

Classification of Serotonin Receptors

open access: yesJournal of Cardiovascular Pharmacology, 1987
The subdivision of serotonin (5-HT) receptors into three classes, designated 5-HT1, 5-HT2, and 5-HT3, has been based on radioligand binding studies and experiments in isolated tissues. As a result of radioligand binding studies, two types of 5-HT recognition sites have been postulated. One site specifically labeled by [3H]5-HT was termed 5-HT1, and the
M, Göthert, E, Schlicker
openaire   +3 more sources

Serotonin receptor mechanisms in anti-depressant action [PDF]

open access: yes, 2003
Bibliography: leaves 221-270.Serotonin neurones have been implicated in the pathophysiology and treatment of clinical depression to a greater degree than any other neurotransmitter.
Quested, Digby John
core   +1 more source

Monoamine Oxidase A Contributes to Serotonin—But Not Norepinephrine-Dependent Damage of Rat Ventricular Myocytes

open access: yesBiomolecules, 2023
Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs).
Jonas Knittel   +6 more
doaj   +1 more source

Food Anticipatory Activity on Circadian Time Scales Is Not Dependent on Central Serotonin: Evidence From Tryptophan Hydroxylase-2 and Serotonin Transporter Knockout Mice

open access: yesFrontiers in Molecular Neuroscience, 2020
A number of studies implicate biogenic amines in regulating circadian rhythms. In particular, dopamine and serotonin influence the entrainment of circadian rhythms to daily food availability.
Christian M. Gallardo   +2 more
doaj   +1 more source

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