Results 21 to 30 of about 143,694 (316)

Molecular and pharmacological characterization of serotonin 5-HT2α and 5-HT7 receptors in the salivary glands of the blowfly calliphora vicina [PDF]

open access: yes, 2012
Secretion in blowfly (Calliphora vicina) salivary glands is stimulated by the biogenic amine serotonin (5-hydroxytryptamine, 5-HT), which activates both inositol 1,4,5-trisphosphate (InsP3)/Ca2+ and cyclic adenosine 3′,5′-monophosphate (cAMP) signalling ...
Walz, Bernd   +23 more
core   +1 more source

Efficacy of serotonin receptor agonists in the treatment of functional dyspepsia: a meta-analysis

open access: yesArchives of Medical Science, 2018
Introduction Functional dyspepsia (FD) is typically treated with serotonin receptor (5-HT) agonists such as cisapride, mosapride, tegaserod and tandospirone citrate.
Man Jin   +5 more
doaj   +1 more source

Classification of Serotonin Receptors

open access: yesJournal of Cardiovascular Pharmacology, 1987
The subdivision of serotonin (5-HT) receptors into three classes, designated 5-HT1, 5-HT2, and 5-HT3, has been based on radioligand binding studies and experiments in isolated tissues. As a result of radioligand binding studies, two types of 5-HT recognition sites have been postulated. One site specifically labeled by [3H]5-HT was termed 5-HT1, and the
M, Göthert, E, Schlicker
openaire   +3 more sources

Endophenotypes and serotonergic polymorphisms associated with treatment response in obsessive-compulsive disorder

open access: yesClinics, 2012
OBJECTIVES: Approximately 40-60% of obsessive-compulsive disorder patients are nonresponsive to serotonin reuptake inhibitors. Genetic markers associated with treatment response remain largely unknown.
Fábio M. Corregiari   +3 more
doaj   +1 more source

The Serotonin Receptor Subtype 5b Specifically Interacts with Serotonin Receptor Subtype 1A

open access: yesFrontiers in Molecular Neuroscience, 2017
Previously, we described the dysregulation of serotonin (5-HT) receptor subtype 5b (5-ht5b) in a mouse model of Rett syndrome (RTT). 5-ht5b has not been extensively studied, so we set out to characterize it in more detail.
Sabine Niebert   +7 more
doaj   +1 more source

The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster

open access: yesFrontiers in Aging, 2022
The conserved neurotransmitter serotonin has been shown to be an important modulator of lifespan in specific nutritional contexts; however, it remained unclear how serotonin signaling influences lifespan under normal conditions.
Allyson S. Munneke   +6 more
doaj   +1 more source

Monoamine Oxidase A Contributes to Serotonin—But Not Norepinephrine-Dependent Damage of Rat Ventricular Myocytes

open access: yesBiomolecules, 2023
Serotonin effects on cardiac hypertrophy, senescence, and failure are dependent either on activation of specific receptors or serotonin uptake and serotonin degradation by monoamine oxidases (MAOs).
Jonas Knittel   +6 more
doaj   +1 more source

Food Anticipatory Activity on Circadian Time Scales Is Not Dependent on Central Serotonin: Evidence From Tryptophan Hydroxylase-2 and Serotonin Transporter Knockout Mice

open access: yesFrontiers in Molecular Neuroscience, 2020
A number of studies implicate biogenic amines in regulating circadian rhythms. In particular, dopamine and serotonin influence the entrainment of circadian rhythms to daily food availability.
Christian M. Gallardo   +2 more
doaj   +1 more source

Serotonin 1B Receptor Gene (HTR1B) Methylation as a Risk Factor for Callous-Unemotional Traits in Antisocial Boys. [PDF]

open access: yesPLoS ONE, 2015
The serotonin system is thought to play a role in the aetiology of callous-unemotional (CU) traits in children. Previous research identified a functional single nucleotide polymorphism (SNP) from the promoter region of the serotonin 1B receptor gene as ...
Caroline Moul   +4 more
doaj   +1 more source

Glycogen Synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission

open access: yesFrontiers in Molecular Neuroscience, 2011
Serotonin is a neurotransmitter with broad functions in brain development, neuronal activity, and behaviors; and serotonin is the prominent drug target in several major neuropsychiatric diseases.
Xiaohua eLi, Abigail ePolter
doaj   +1 more source

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