Results 11 to 20 of about 1,423,567 (298)
Serotonin reuptake inhibitors and cardiovascular disease [PDF]
, 2005 Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Noble, M. +2 more
core +8 more sources
Characterization of the 5-HT(7) receptor as a new therapeutic target for the treatment of pain [PDF]
, 2012 [eng] The work showed in this Thesis has been part of the “5-HT7 and neuropathic pain” project in the pharmaceutical company Esteve. Thus, the aim of this Thesis was in line with the goal of the 5-HT7 project at Esteve, focused on drug discovery of 5-HT7
Brenchat Barberà, Àlex
core +6 more sources
The Effects of Serotonin Receptor Antagonists on Contraction and Relaxation Responses Induced by Electrical Stimulation in the Rat Small Intestine [PDF]
, 2014 Background: The main source of 5-HT in body is in enterchromafin cells of intestine, different studies mentioned different roles for endogenous 5-HT and receptors involved and it is not clearified the mechanism of action of endogenous 5-HT. Objectives:
Javid, Farideh A. +2 more
core +5 more sources
Modulation of anxiety by cortical serotonin 1A receptors
Frontiers in Behavioral Neuroscience, 2015 Serotonin (5-HT) plays an important role in the modulation of behavior across animal species. The serotonin 1A receptor (Htr1a) is an inhibitory G-protein coupled receptor that is expressed both on serotonin and non-serotonin neurons in mammals.
Lukasz ePiszczek +4 more
doaj +1 more source
Expression of Serotonin Receptors in Bone [PDF]
Journal of Biological Chemistry, 2001 The 5-hydroxytryptamine (5-HT) receptors 5-HT(2A), 5-HT(2B), and 5-HT(2C) belong to a subfamily of serotonin receptors. Amino acid and mRNA sequences of these receptors have been published for several species including man. The 5-HT(2) receptors have been reported to act on nervous, muscle, and endothelial tissues.
Westbroek, I. +4 more
openaire +5 more sources
Frontiers in Cellular Neuroscience, 2022 Depression and anxiety are common, debilitating psychiatric conditions affecting millions of people throughout the world. Current treatments revolve around selective serotonin reuptake inhibitors (SSRIs), yet these drugs are only moderately effective at ...
Nikita Deo, Gregory Redpath
doaj +1 more source
Serotonin Receptors: Genetic insights into serotonin function [PDF]
Current Biology, 1995 Targeted disruption of the genes for the 5-HT1B and 5-HT2C serotonin receptors and monoamine oxidase A have confirmed pharmacological experiments and revealed unexpected behavioral roles for serotonin.
Heath, Mark J.S., Hen, René
openaire +2 more sources
Frontiers in Neuroscience, 2015 In the Chagas disease vector, Rhodnius prolixus, two diuretic hormones act synergistically to dramatically increase fluid secretion by the Malpighian tubules (MTs) during the rapid diuresis that is initiated upon engorgement of vertebrate blood.
Jean-Paul V Paluzzi +10 more
doaj +1 more source
Frontiers in Pharmacology, 2014 Investigation of the effects of serotonin on memory formation in the chick revealed an action on at least two 5HT receptors. Serotonin injected intracerebrally produced a biphasic effect on memory consolidation with enhancement at low doses and ...
Marie Elizabeth Gibbs, Leif eHertz
doaj +1 more source
A physiologic role for serotonergic transmission in adult rat taste buds. [PDF]
PLoS ONE, 2014 Of the multiple neurotransmitters and neuropeptides expressed in the mammalian taste bud, serotonin remains both the most studied and least understood.
Luc Jaber +3 more
doaj +1 more source