Results 241 to 250 of about 207,072 (360)

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

open access: yesFood Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey. [PDF]

open access: yesPharmaceuticals (Basel)
Ghafir El Idrissi I   +3 more
europepmc   +1 more source

The Structural Determinants for α1-Adrenergic/Serotonin Receptors Activity among Phenylpiperazine-Hydantoin Derivatives. [PDF]

open access: yesMolecules, 2021
Kucwaj-Brysz K   +8 more
europepmc   +1 more source

Exploring the Potential of Coumarin Derivatives on Serotonin Receptors 5-HT<sub>1A</sub> and 5HT<sub>2A</sub>. [PDF]

open access: yesInt J Mol Sci
Ostrowska K   +8 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Zacopride stimulates 5-HT4 serotonin receptors in the human atrium. [PDF]

open access: yesNaunyn Schmiedebergs Arch Pharmacol
Neumann J, Hesse C, Hofmann B, Gergs U.
europepmc   +1 more source

Probiotics‐derived postbiotics improve host metabolic syndrome by activating the adipocyte thermogenic signaling pathway in high‐fat diet‐fed mice

open access: yesiMetaOmics, EarlyView.
This schematic illustrates how probiotics‐derived postbiotics (PLBK®1–5) combat high‐fat diet‐induced obesity. Postbiotics remodel gut microbiota, boosting beneficial metabolites. These metabolites activate adipocyte thermogenesis (Ucp1/AMPK pathway), resulting in reduced body weight, improved insulin sensitivity, and alleviated hepatic steatosis in ...
Ye Tian   +7 more
wiley   +1 more source

Mosapride stimulates human 5-HT4-serotonin receptors in the heart. [PDF]

open access: yesNaunyn Schmiedebergs Arch Pharmacol
Neumann J, Hesse C, Hofmann B, Gergs U.
europepmc   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

open access: yesiNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu   +10 more
wiley   +1 more source

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