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Critical Care Clinics, 1997
Serotonin syndrome is a potentially life-threatening complication of psychopharmacologic drug therapy. The syndrome is produced most often by the concurrent use of two or more drugs that increase brainstem serotonin activity and is often unrecognized because of the varied and nonspecific nature of its symptomatology. Serotonin syndrome is characterized
Ivanuša, Zrinka +2 more
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Serotonin syndrome is a potentially life-threatening complication of psychopharmacologic drug therapy. The syndrome is produced most often by the concurrent use of two or more drugs that increase brainstem serotonin activity and is often unrecognized because of the varied and nonspecific nature of its symptomatology. Serotonin syndrome is characterized
Ivanuša, Zrinka +2 more
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Serotonin Syndrome and the Anaesthetist [PDF]
Anaesthesia and Intensive Care, 2005 Serotonin syndrome results from excessive activation of serotonin (5-hydroxytryptamine; 5-HT) receptors in the nervous system, on the surface of platelets, and on the vascular endothelium. The clinical manifestations are a triad of altered conscious state, autonomic dysfunction, and neuromuscular excitability. Clinical diagnostic criteria remain poorly
David Story
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New England Journal of Medicine, 2005
The serotonin syndrome is a potentially life-threatening drug reaction that may result from therapeutic medication use, self-poisoning, or interactions between drugs.
Edward W, Boyer, Michael, Shannon
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The serotonin syndrome is a potentially life-threatening drug reaction that may result from therapeutic medication use, self-poisoning, or interactions between drugs.
Edward W, Boyer, Michael, Shannon
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Neurology, 1995
We describe a patient treated with trazodone, isocarboxazid, and methylphenidate hydrochloride who developed confusion, agitation, poor concentration, rigidity, myoclonus, involuntary movements, orthostatic hypotension, and hyperreflexia. CK was normal, and the syndrome resolved spontaneously over 12 hours.
R A, Bodner, T, Lynch, L, Lewis, D, Kahn
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We describe a patient treated with trazodone, isocarboxazid, and methylphenidate hydrochloride who developed confusion, agitation, poor concentration, rigidity, myoclonus, involuntary movements, orthostatic hypotension, and hyperreflexia. CK was normal, and the syndrome resolved spontaneously over 12 hours.
R A, Bodner, T, Lynch, L, Lewis, D, Kahn
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Overview of Serotonin Syndrome
Annals of Clinical Psychiatry, 2012Background Serotonin syndrome (SS) is a rare and potentially lifethreatening toxic state caused by an adverse drug reaction that leads to excessive central and peripheral serotonergic activity. This excessive serotonin hyperstimulation may be secondary to 1 standard therapeutic dose of a single agent, inadvertent interactions ...
Mohammad M, Iqbal +3 more
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Emergency Medicine Clinics of North America, 1997
The serotonin syndrome is characterized by mental status changes and a variety of autonomic and neuromuscular manifestations. Its duration is usually brief, resolving within hours provided that the inciting agent has been discontinued. In most cases, two or more types of medications known to increase the activity of serotonin at the 5-HT1A receptor are
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The serotonin syndrome is characterized by mental status changes and a variety of autonomic and neuromuscular manifestations. Its duration is usually brief, resolving within hours provided that the inciting agent has been discontinued. In most cases, two or more types of medications known to increase the activity of serotonin at the 5-HT1A receptor are
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Serotonin Syndrome in Pregnancy
Nursing for Women's Health, 2015Millions of people take selective serotonin reuptake inhibitors (SSRIs) for depression and anxiety, so nurses and other clinicians need to be aware of the potential for serotonin toxicity and serotonin syndrome. These conditions can occur when women taking SSRIs are given additional medications in the labor and birth or postpartum settings.
Cheryl K, Roth +2 more
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Journal of Neuroscience Nursing, 2006
Serotonin syndrome is a preventable, drug-related complication that results from increased brainstem serotonin activity, usually precipitated by the use of one or more serotonergic drugs. Its clinical presentation consists of autonomic dysfunction, alteration in mental status, and neuromuscular disorder.
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Serotonin syndrome is a preventable, drug-related complication that results from increased brainstem serotonin activity, usually precipitated by the use of one or more serotonergic drugs. Its clinical presentation consists of autonomic dysfunction, alteration in mental status, and neuromuscular disorder.
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Linezolid and Serotonin Syndrome
Psychosomatics, 2001Received March 21, 2001; accepted March 29, 2001. From Eastern Virginia Medical School, Department of Psychiatry and Behavioral Sciences, 825 Fairfax Avenue, Norfolk, Virginia 23507. Address correspondence and reprint requests to Dr. Pushkin, Associate Professor of Clinical Psychiatry, Director Consultation & Liaison Psychiatry, EVMS; E-mail address ...
S, Lavery +3 more
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