Results 101 to 110 of about 141,303 (265)

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

open access: yesBiotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing   +2 more
wiley   +1 more source

The serotype of Rotavirus.

open access: yesUirusu, 1992
Urasawa, Shozo   +2 more
openaire   +3 more sources

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

open access: yesBiotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera   +8 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

open access: yesEpilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer   +7 more
wiley   +1 more source

Global Warming and Rising Threat of Dengue Fever: Expectations in Disease Management

open access: yesIndian Journal of Public Health
Arbovirus-borne dengue fever remains a global public health threat. The actual burden of dengue infection may be underestimated due to undiagnosed or misdiagnosed fever cases.
Swati Sinha, Auley De, Ajanta Halder
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

open access: yesFood Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei   +4 more
wiley   +1 more source

The Comparative Full-Length Genome Characterization of African Swine Fever Virus Detected in Thailand

open access: yesAnimals
African swine fever virus (ASFV) has been responsible for the globally devastating epidemics in wild and domesticated pigs. Of the 24 identified ASFV genotypes, genotype II is the primary cause for the pandemic occurring in Europe and Asia since its ...
Muhammad Salman   +14 more
doaj   +1 more source

Economic Impact of Dengue Virus in Mexico Over One Decade: A Systematic Literature Review (2010–2020)

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Background Dengue is a major mosquito‐borne viral disease worldwide, imposing significant healthcare burden on governments in countries where it is endemic, such as Mexico. This systematic review focused on studies reporting the cost of dengue in Mexico during 2010–2020.
Gilberto Sánchez‐González   +2 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

open access: yesiNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu   +22 more
wiley   +1 more source

Research progress into the principles and methods underlying capsular typing of Glaesserella parasuis

open access: yesVeterinary Research
Glaesserella parasuis (GPS) is an important bacterial pathogen of swine. Serotype identification has presented a bottleneck in GPS research since it was first identified as the pathogen causing Glässer’s disease in pigs in 1910.
Yaxin Zhu   +4 more
doaj   +1 more source

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