Results 81 to 90 of about 239,401 (300)

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

open access: yesAdvanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji   +13 more
wiley   +1 more source

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

open access: yes, 2009
OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation. METHODS: Case-control study in
Adegbola, Richard A   +8 more
core   +1 more source

Developing a serocorrelate of protection against invasive group B streptococcus disease in pregnant women: a feasibility study. [PDF]

open access: yes, 2019
BACKGROUND: Group B streptococcus is the leading cause of infection in infants. Currently, intrapartum antibiotic prophylaxis is the major strategy to prevent invasive group B streptococcus disease.
Andrews, N   +16 more
core   +1 more source

Detection of G12 Human Rotaviruses in Nepal

open access: yesEmerging Infectious Diseases, 2007
Of 731 stool specimens collected from children with diarrhea in Kathmandu, Nepal, from August 2004 through July 2005, 170 (23.3%) tested positive for rotavirus. Reverse transcription–PCR, including a revised G12-specific primer set, identified 56 (32.9%)
Sher Bahadur Pun   +7 more
doaj   +1 more source

Serotyping v1

open access: yes, 2021
Serotyping of Streptococcus agalactiae isolates were analized by ImmuLex® Strep-B Latex, Statens Serum Institut,Copenhagen, Denmark, classifying in 1a,1b, II, III, IV, V, VII, VIII y IX.
openaire   +1 more source

Gel Diffusion Studies on Serotype and Serotype Transformation in Paramecium [PDF]

open access: yesJournal of General Microbiology, 1959
SUMMARY: Antigens G and E of stock 28 variety 2 of Paramecium aurelia show cross-reactions with their respective antisera in immobilization and gel diffusion tests. In immobilization tests the anti-E serum P, no. 132, shows the strongest cross-reaction; in gel diffusion tests the anti-G serum P, no. 130, cross reacts more strongly.
E, BALBINDER, J R, PREER
openaire   +2 more sources

NUP85 Mediates Endoplasmic Reticulum Stress through the USP47/ASK1 Signaling Pathway to Regulate the Progression of Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang   +11 more
wiley   +1 more source

Characterization of virulence factors in the newly described Salmonella enterica serotype Keurmassar emerging in Senegal (sub-Saharan Africa) [PDF]

open access: yes, 2006
From 2000 to 2001, nine strains of Salmonella enterica belonging to the new serotype Keurmassar have been isolated from human and poultry samples at the Senegalese National Salmonella and Shigella Reference Laboratory at the Pasteur Institute, in Dakar.
Aidara-Kane, Awa   +5 more
core  

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Invasive Streptococcus pneumoniae in Children, Malawi, 2004–2006

open access: yesEmerging Infectious Diseases, 2011
Of 176 invasive Streptococcus pneumoniae isolates from children in Malawi, common serotypes were 1 (23%), 6A/B (18%), 14 (6%), and 23F (6%). Coverage with the 7-valent pneumococcal conjugate vaccine (PCV) was 39%; PCV10 and PCV13 increased coverage to 66%
Jennifer E. Cornick   +6 more
doaj   +1 more source

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