Results 131 to 140 of about 241,652 (335)
Two New Salmonella Serotypes Isolated from Man [PDF]
, 1943 Kenneth M. Wheeler, Earle K. Borman
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Techno‐Economic Analysis of Membrane‐Based Purification Platforms for AAV Vector Production
Biotechnology and Bioengineering, EarlyView.ABSTRACT Technologies for large‐scale manufacturing of viral vectors for gene therapies, such as tangential flow filtration and membrane chromatography, are under development. In these early stages of process development, techno‐economic analyses are useful for identifying membrane properties yielding the greatest impact on process performance. In this
Juan J. Romero +6 more
wiley +1 more source
Epizootiološko istraživanje slinavke i šapa u Sudanu: stanje nakon dva desetljeća [PDF]
, 2010 In order to update information on the situation regarding foot and mouth disease (FMD) in the Sudan, a serosurvey and disease survey were conducted. Recently collected data on FMD in the Sudan showed that FMD is a major constraint to animal production in
Mohammed A. G. Alamin +3 more
core +2 more sources
Enrichment of Full AAV2 Using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP)
Biotechnology and Bioengineering, EarlyView.The multicolumn countercurrent solvent gradient purification (MCSGP) method was evaluated as a method to enhance the separation of empty and full capsids during AAV2 purification. The results demonstrated an enrichment of full AAV2 particles using MCSGP.
Julia M. Müller +9 more
wiley +1 more source
Immune Response of Cattle to Different Serotype Antigens in Monovalent and Trivalent Foot-and-Mouth Disease Vaccines [PDF]
, 1969 J. H. Graves
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The complexity of serotype replacement of pneumococci [PDF]
Human Vaccines & Immunotherapeutics, 2019 Pneumococci respond extremely rapidly to the vaccine pressure created by the conjugate vaccines (PCVs). Vaccine serotypes are disappearing, meanwhile new, often previously very rare types are emerging, and it is difficult to establish what makes certain serotypes more successful in replacement.
openaire +4 more sources
Iterative hybrid model based optimization of rAAV production
Biotechnology Progress, EarlyView.Abstract Changes in serotype or genetic payload of recombinant adeno associated virus (rAAVs) gene therapies require adapting the transfection conditions of the upstream HEK293 cultivations. This study adopts an iterative model‐based experiment design approach, where increasing data availability is leveraged to evolve models of different complexity ...
Claudio Müller +7 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo +6 more
wiley +1 more source
Brazilian Archives of Biology and Technology, 2013 The objective of this study was to analyze the genotypic diversity, frequency of serotypes and the detection of mutacins from Streptococcus mutans isolates in caries-free and caries-active individuals.A total of 260 S. mutans isolated from 28 individuals
Miula Portelinha Braga +5 more
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