Results 141 to 150 of about 241,652 (335)
ABSTRACT The ICH Q14 guideline introduces a structured framework for analytical method development based on Analytical Quality by Design (AQbD) principles, aiming to ensure robust, reliable, and fit‐for‐purpose methods throughout the product lifecycle.
Ewoud van Tricht+1 more
wiley +1 more source
Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang+4 more
wiley +1 more source
Abstract Outbreaks of bacterial infections in aquaculture have emerged as significant threats to the sustainable production of rainbow trout (Oncorhynchus mykiss) worldwide. Understanding the dynamics of these outbreaks and the bacteria involved is crucial for implementing effective management strategies. This comprehensive review presents an update on
Muhammed Duman+3 more
wiley +1 more source
Escherichia coli pathotype virulotyping to assess if combined top soil improver and water inputs would potentially lead to hybrid strains with shuffled virulence features in ready‐to‐eat vegetables. This is to support the transition toward safe and sustainable food production systems.
Giorgia Barbieri+9 more
wiley +1 more source
Abstract Bacterial coldwater disease (BCWD), caused by Flavobacterium psychrophilum, results in significant losses among multiple salmonid (family Salmonidae) species. Molecular epidemiology and serotyping studies have suggested that some variants are host specific; however, these associations have not been evaluated by cross‐challenging fish species ...
Christopher Knupp, Thomas P. Loch
wiley +1 more source
H SEROTYPE DIFFERENTIATION IN TETRAHYMENA [PDF]
David L. Nanney+3 more
openalex +1 more source
THE RELATIONSHIP BETWEEN THE MATING TYPE AND THE H SEROTYPE SYSTEMS IN TETRAHYMENA [PDF]
David L. Nanney
openalex +1 more source
In this study, we found evidence of phage‐mediated horizontal transfer of virulence genes in Salmonella enterica in global habitats from a molecular evolutionary perspective. Notably, csrA, a global regulator in Salmonella enterica, curbed horizontal gene transfer by inhibiting the cyclization and release of prophage.
Tianjing She+9 more
wiley +1 more source
Bordetella pertussis Serotypes in the United States [PDF]
Grace Eldering+3 more
openalex +1 more source