Results 191 to 200 of about 206,874 (310)

Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species

Aging Cell, EarlyView.
This study demonstrates that reducing the enzyme topoisomerase Top2 or its mammalian homolog TOP2B promotes longevity across multiple species, including yeast, worms, and mice. At the cellular/molecular level, TOP2B reduction mitigates the major cellular aging hallmarks such as epigenetic alterations, cell senescence, lysosomal biogenesis, and ...
Man Zhu, Meng Ma, Lunan Luo, Feiyang Li, Jiashun Zheng, Yan Pan, Lu Yang, Ying Xiao, Ziyan Wang, Bo Xian, Yi Zheng, Hao Li, Jing Yang   +12 more
wiley   +1 more source

Identification of All Dengue Serotypes in Nepal

Emerging Infectious Diseases, 2008
Sarala Malla, Garib D. Thakur, Sanjaya K. Shrestha, Manas K. Banjeree, Laxmi B. Thapa, Gyanendra Gongal, Prakash Ghimire, Bishnu P. Upadhyay, Purosotam Gautam, Shyam Khanal, Ananda Nisaluk, Richard G. Jarman, Robert V. Gibbons   +12 more
doaj   +1 more source

Pneumococcal Serotypes and Virulence [PDF]

The Journal of Infectious Diseases, 2006
openaire   +3 more sources

Senescent Macrophages Promote Age‐Related Revascularization Impairment by Increasing Antiangiogenic VEGF‐A165B Expression

Aging Cell, EarlyView.
The underlying mechanisms of age‐related revascularization impairment are not clear. Our research firstly identified that macrophages were more senescent in the ischemic skeletal muscle of old mice and senescent macrophages could inhibit revascularization.
Minghong Chen, Junyu Chen, Yu Liu, Xuerui Wang, Meilian Yao, Jing Chen, Jian Zhang, Qun Huang   +7 more
wiley   +1 more source

Increasing incidence of serotype 38 invasive pneumococcal disease driven by the ST393 clone among children, Denmark 2022-2024. [PDF]

Sci Rep
Schjørring CB, Lomholt FK, Valentiner-Branth P, Dalby T, Fuursted K, Slotved HC, Harboe ZB.   +6 more
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Comparative genomic analysis of Streptococcus suis sequence type 105 and development of a PCR diagnostic tool. [PDF]

PLoS One
Boueroy P, Chopjitt P, Borthong J, Wongsurawat T, Jenjaroenpun P, Duangjanchot R, Saiboonjan B, Hatrongjit R, Kerdsin A.   +8 more
europepmc   +1 more source

The prevalence, serotypes and antibiograms of Salmonella isolates on Thoroughbred stud farms in New South Wales and Victoria

Australian Veterinary Journal, EarlyView.
Salmonella enterica subsp. enterica is responsible for substantial morbidity and mortality within horse populations, worldwide. The prevalence of Salmonella shedding in faeces has largely been reported in hospital settings, with limited information from general horse populations.
SP McTernan, J Heller, JR Clulow, L Gannon, R Huang, N Tidd, A Blishen, KJ Hughes   +7 more
wiley   +1 more source

Age-related decline in IgM responses associate with reduced opsonophagocytic activity following PCV13 vaccination. [PDF]

NPJ Vaccines
Visser M, van Beek J, Tcherniaeva I, van Rooijen DM, Beckers L, Bijvank E, de Jonge MI, Lockhart SP, Pride MW, Rots N, van Baarle D, den Hartog G, Buisman AM.   +12 more
europepmc   +1 more source

T SEROTYPE DIFFERENTIATION IN TETRAHYMENA [PDF]

Genetics, 1967
openaire   +3 more sources