Results 231 to 240 of about 219,974 (370)

Chronic optogenetic stimulation of dentate gyrus granule cells in mouse organotypic slice cultures synaptically drives mossy cell degeneration

open access: yesEpilepsia, EarlyView.
Abstract Objective Degeneration of hilar mossy cells in the dentate gyrus is an important hallmark of hippocampal sclerosis and is often observed in patients with temporal lobe epilepsy. To understand the pathogenesis of hippocampal sclerosis and develop novel neuroprotective treatments, it is critical to determine the mechanistic processes of mossy ...
Carolin Christina Koretz   +5 more
wiley   +1 more source

Clinical and evidence-based considerations for choosing a pneumococcal conjugate vaccine in India: A narrative review. [PDF]

open access: yesHum Vaccin Immunother
Yewale V   +4 more
europepmc   +1 more source

Optogenetically‐induced sustained hypothalamic hyperexcitability impairs memory via thalamic spread

open access: yesEpilepsia, EarlyView.
Abstract Objective Clinical investigators have hypothesized that interictal epileptiform discharges (IEDs) generated by hypothalamic hamartoma (HH) lead to cognitive dysfunction in patients with drug‐resistant gelastic seizures. Herein we provide causal evidence supporting this hypothesis by demonstrating that excitatory neural bursts, when propagating
Masaki Sonoda   +11 more
wiley   +1 more source

Invasive Serotype 35B Pneumococci Including an Expanding Serotype Switch Lineage [PDF]

open access: yesEmerging Infectious Diseases, 2018
Liset Olarte   +11 more
openaire   +4 more sources

Botulinum toxin type A treatment for a parotid gland injury in two adult horses

open access: yesEquine Veterinary Education, EarlyView.
Summary The most common disorder affecting the salivary glands in horses is trauma to the parotid gland or duct. Several management techniques have been described, each with their own set of complications. The objective of this case report was to describe the direct injection of botulinum toxin type A into the parotid gland and its outcome in two ...
C. Jimenez, F. Comino, D. Gorvy
wiley   +1 more source

Serotype replacement in disease after pneumococcal vaccination

open access: yesThe Lancet, 2011
D. Weinberger, R. Malley, M. Lipsitch
semanticscholar   +1 more source

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