Results 41 to 50 of about 234,349 (284)

Microarray for serotyping of Bartonella species [PDF]

BMC Microbiology, 2007
AbstractBackgroundBacteria of the genusBartonellaare responsible for a large variety of human and animal diseases. Serological typing ofBartonellais a method that can be used for differentiation and identification ofBartonellasubspecies.ResultsWe have developed a novel multiple antigenic microarray to serotypeBartonellastrains and to select poly and ...
Cyrille J. Bonhomme, Didier Raoult, Claude Nappez   +2 more
openaire   +4 more sources

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

A synthetic biology approach for a vaccine platform against known and newly emerging serotypes of bluetongue virus [PDF]

, 2014
Bluetongue is one of the major infectious diseases of ruminants and is caused by Bluetongue virus (BTV), an arbovirus existing in nature in at least 26 distinct serotypes. Here, we describe the development of a vaccine platform for BTV.
Brunet, Silvie, Hamers, Claude, Hudelet, Pascal, Nunes, Sandro Filipe, Palmarini, Massimo, Ratinier, Maxime, Shaw, Andrew   +6 more
core   +2 more sources

Ubiquitination‐Dependent LLGL2 Degradation Drives Colorectal Cancer Progression via THBS3 mRNA Stabilization

Advanced Science, EarlyView.
During the progression of CRC, MDM2, as an E3 ubiquitin ligase, promotes the degradation of the LLGL2 protein. Reduced expression of the LLGL2 protein leads to the loss of support for the CNOT1 protein, decreasing the degradation of THBS3 mRNA. The increased THBS3 further activates the PI3K‐Akt pathway, promoting the proliferation and metastasis of CRC.
Jiayan Huang, Tiantian Zhang, Huimin Li, Zidan Li, Shuangshuang Yin, Yiman Liu, Chunze Zhang, Yuling Qiu, Haiyang Yu   +8 more
wiley   +1 more source

Developing a serocorrelate of protection against invasive group B streptococcus disease in pregnant women: a feasibility study. [PDF]

, 2019
BACKGROUND: Group B streptococcus is the leading cause of infection in infants. Currently, intrapartum antibiotic prophylaxis is the major strategy to prevent invasive group B streptococcus disease.
Andrews, N, Carreras-Abad, C, Cochet, M, Djennad, A, Hall, T, Hamid, R, Heath, P, Khalil, A, Le Doare, K, Peregrine, E, Planche, T, Plumb, J, Ramkhelawon, L, Sheridan, E, Sivarajan, S, Vinayakarao, L, Winchester, S   +16 more
core   +1 more source

A previously undescribed Salmonella serotype: S. sp. serotype rideau [PDF]

International Journal of Systematic Bacteriology, 1967
SUMMARY A new Salmonella serotype (1, 3, 19; fg:-) was described and the designation S. sp. serotype rideau was assigned to it. The culture was isolated in the routine screening of military personnel from Tanzania recently arrived in Canada for special training.
Joseph A. Yurack, Rhoda M. Laidley, Walter C. Harris   +2 more
openaire   +2 more sources

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: A longitudinal household study [PDF]

, 2005
Background. Natural immunity to Streptococcus pneumoniae is thought to be induced by exposure to S. pneumoniae or cross-reactive antigens. No longitudinal studies of carriage of and immune responses to S.
Andrews, N, Ashton, L, Edmunds, J, Gay, N, George, R, Goldblatt, D, Hussain, M, Kayhty, H, Melegaro, A, Miller, E, Pebody, R, Soininen, A, Virta, C   +12 more
core  

Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]

, 2011
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith, Aspa, Austrian, Avery, Blake, Cecil, Chris Robertson, David Greenhalgh, Diggle, Donald Inverarity, Giles F. S. Edwards, Guimbao Bescós, Huss, Inostroza, Jim McMenamin, Johanna M. C. Jefferies, Karen Lamb, Kendrick, Lamb, Martin, Mathew Diggle, Shapiro, Stuart C. Clarke, Tim J. Mitchell, Weiss   +24 more
core   +3 more sources

Serotyping of Acinetobacter calcoaceticus. [PDF]

Journal of Clinical Pathology, 1984
Serotyping of Acinetobacter calcoaceticus by direct immunofluorescence and a capsule swelling reaction is described. One hundred isolates, including 12 from an outbreak in a neonatal department, were studied. Ninety five per cent of the isolates were typable by immunofluorescence and could be divided into 30 separate types, but 42.1% of typable strains,
G Ayliffe, B C Das
openaire   +3 more sources