Results 71 to 80 of about 219,974 (370)

Discovery of Novel Pneumococcal Serotype 35D, a Natural WciG-Deficient Variant of Serotype 35B

Journal of Clinical Microbiology, 2017
Pneumococcus (Streptococcus pneumoniae) remains a significant cause of morbidity and mortality, especially among those at the extremes of age. Its capsular polysaccharide is essential for systemic virulence.
K. A. Geno, Jamil S. Saad, Moon H. Nahm
semanticscholar   +1 more source

Two New Salmonella Serotypes (Serotype malakal and Serotype khartoum) Isolated from Dogs [PDF]

International Journal of Systematic Bacteriology, 1972
Two new Salmonella serotypes, Salmonella sp. serotype malakal and Salmonella sp. serotype khartoum, have been isolated from mesenteric lymph nodes of apparently healthy dogs in the Sudan, and they belong to Salmonella subgenus I. The antigenic formulae of these serotypes are: S. malakal = 16: e,h: 1,2; S. khartoum = (3),(15), 34: a : 1,7.
Quddus A. Khan, R. Rohde
openaire   +2 more sources

Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting

Advanced Materials, EarlyView.
CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu, Won Joon Kim, Hyunjin Lee, Xiaoping Bao, Pilnam Kim   +4 more
wiley   +1 more source

Gene Therapy Using Recombinant AAV Type 8 Vector Encoding TNAP‐D10 Improves the Skeletal Phenotypes in Murine Models of Osteomalacia

JBMR Plus, Volume 7, Issue 1, January 2023., 2023
ABSTRACT Hypophosphatasia (HPP), caused by loss‐of‐function mutations in the ALPL gene encoding tissue‐nonspecific alkaline phosphatase (TNAP), is characterized by skeletal and dental hypomineralization that can vary in severity from life‐threatening to milder manifestations only in adulthood.
Flavia Amadeu de Oliveira, Fatma F. Mohamed, Yuka Kinoshita, Sonoko Narisawa, Colin Farquharson, Koichi Miyake, Brian L Foster, Jose Luis Millan   +7 more
wiley   +1 more source

Serotypes of Aggregatibacter actinomycetemcomitans in relation to periodontal status and assessment of leukotoxin in periodontal disease: A clinico-microbiological study

Journal of Indian Society of Periodontology, 2018
Context: Aggregatibacter actinomycetemcomitans (A.a) serotypes may add some important information of the pathogenetic background of periodontal infections. A.a leukotoxin is an important virulence factor in the pathogenesis of periodontal disease and its
Sudhakar Shuntikudege Suprith, Swati Setty, Kishore Bhat, Srinath Thakur   +3 more
doaj   +1 more source

Determining Streptococcus suis serotype from short-read whole-genome sequencing data

BMC Microbiology, 2016
BackgroundStreptococcus suis is divided into 29 serotypes based on a serological reaction against the capsular polysaccharide (CPS). Multiplex PCR tests targeting the cps locus are also used to determine S.
T. Athey, S. Teatero, S. Lacouture, D. Takamatsu, M. Gottschalk, N. Fittipaldi   +5 more
semanticscholar   +1 more source

Lipopolysaccharide‐Induced Bone Loss in Rodent Models: A Systematic Review and Meta‐Analysis

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 198-213, January 2023., 2023
ABSTRACT Osteoporosis has traditionally been characterized by underlying endocrine mechanisms, though evidence indicates a role of inflammation in its pathophysiology. Lipopolysaccharide (LPS), a component of gram‐negative bacteria that reside in the intestines, can be released into circulation and stimulate the immune system, upregulating bone ...
Kirsten N. Bott, Evelyn Feldman, Russell J. de Souza, Elena M. Comelli, Panagiota Klentrou, Sandra J. Peters, Wendy E. Ward   +6 more
wiley   +1 more source

Qualitative and Quantitative Analysis of Salmonella spp. in Broilers Technological Processing and Determination of a Performance Objective (PO) for Frozen Chicken Breast [PDF]

Brazilian Journal of Poultry Science
The present study investigated the frequency, level of contamination and serotyping of Salmonella strains isolated from broiler flocks in different processing sites and the fulfillment of a Performance Objective (PO) in frozen chicken breasts, as a risk ...
SCA Machado, VLA Pereira, MHC Aquino, A Giombeli, DP Rodrigues, ER Nascimento   +5 more
doaj   +2 more sources

Quantitative Prediction of Linear B-Cell Epitopes [PDF]

Biomedical Statistics and Informatics. Vol. 2, No.1, 2017, pp.1-3, 2017
In scientific literature, there are many programs that predict linear B-cell epitopes from a protein sequence. Each program generates multiple B-cell epitopes that can be individually studied. This paper defines a function called that combines results from five different prediction programs concerning the linear B-cell epitopes (ie., BebiPred ...
arxiv   +1 more source

Serotype 3 Remains the Leading Cause of Invasive Pneumococcal Disease in Adults in Portugal (2012–2014) Despite Continued Reductions in Other 13-Valent Conjugate Vaccine Serotypes

Frontiers in Microbiology, 2016
Since 2010 the 13-valent pneumococcal conjugate vaccine (PCV13) replaced the 7-valent vaccine (PCV7) as the leading pneumococcal vaccine used in children through the private sector. Although, neither of the PCVs were used significantly in adults, changes
Andreia N. Horácio, C. Silva-Costa, Joana P. Lopes, M. Ramirez, J. Melo-Cristino, Teresa Marília Rui Ana Buschy Henrique Ana Cristina Hermí Vaz Gião Ferreira Fonseca Oliveira Silva Costa Sil   +5 more
semanticscholar   +1 more source